低血糖对2型糖尿病患者的影响1ppt课件.pptVIP

* Asymptomatic Episodes of Hypoglycemia May Go Unreported In clinical studies of continuous glucose monitoring (CGM), episodes of hypoglycemia have been found to go unrecognized.1–3 Chico et al1 used CGM to measure the frequency of unrecognized episodes of hypoglycemia in patients with type 1 (n=40) and type 2 (n=30) diabetes. CGM detected unrecognized hypoglycemic events in 55.7% of all patients. In the subset of patients with type 2 diabetes, CGM detected hypoglycemic events in 46.6% of patients.1 Other researchers have reported similar findings.2,3 Purpose To show the extent to which episodes of hypoglycemia may go unnoticed. TakeawayMany asymptomatic episodes of hypoglycemia go unreported in patients with diabetes. References 1. Chico A, Vidal-Ríos P, Subirà M, Novials A. The continuous glucose monitoring system is useful for detecting unrecognized hypoglycemias in patients with type 1 and type 2 diabetes but is not better than frequent capillary glucose measurements for improving metabolic control. Diabetes Care. 2003;26(4):1153–1157. 2. Weber KK, Lohmann T, Busch K, Donati-Hirsch I, Riel R. High frequency of unrecognized hypoglycaemias in patients with type 2 diabetes is discovered by continuous glucose monitoring. Exp Clin Endocrinol Diabetes. 2007;115(8):491–494. 3. Zick R, Petersen B, Richter M, Haug C. Comparison of continuous blood glucose measurement with conventional documentation of hypoglycemia in patients with type 2 diabetes on multiple daily insulin injection therapy. Diab Technol Ther. 2007;9(6):483–492. * Risk Factors and Consequences of Hypoglycemia in Type 2 Diabetes The most common risk factors of hypoglycemia in type 2 diabetes include1 Use of insulin secretagogues and insulin therapy (most common) Missed or irregular meals Advanced age Duration of diabetes Impaired awareness of hypoglycemia Note that some of these factors are interrelated. For example, long-term diabetes is inevitably associated with increasing age, and