顾勇_Integration of sensory and motor function (19,20).pptVIP

* Probability Combined Amount of Improvements X If Case 1: If Case 2: X Combined Probability ? 0.7? Maximum effect! Behavioral Evidence for Multi-Sensory Cue Integration Gu et al., (2008) NN Populations of neurons with Poisson-like spiking statistics can implement Bayes-optimal cue integration if each neuron simply sums its multi-sensory inputs Linear summation Firing rate weights do not change with cue reliability Firing rate weights = 1 for all coherences What do we expect from neurons? Ma, Beck, Latham Pouget, Nature Neurosci (2006) Multisensory integration in subcortical area: the superior colliculus often emphasized non-linear (super-additive) interactions Stein Stanford, Nature Reviews Neuroscience, 2008 Sub-additive in cortex Gu et al., (2008) Multisensory integration: a normalization Model Ohshiro et al., (2011) NN Presentation: Armstrong KM, Chang MH, Moore T. (2003) Selection and maintenance of spatial information by frontal eye field neurons. Nature 2) Afraz SR, Kiani R, Esteky H. (2006) Microstimulation of inferotemporal cortex influences face categorization. Nature Reppas JB, Newsome WT. (2007) Brain stimulation: feeling the buzz. Current Biology * * * A 训练：每天用2，3指顶端一小时，偶尔用4指。皮层代表区变大。 B 皮层神经元的感受野变多 （训练后感受野密度大）。 * A 训练：每天用2，3指顶端一小时，偶尔用4指。皮层代表区变大。 B 皮层神经元的感受野变多 （训练后感受野密度大）。 * * * * * * * * * * * * * * * Stimulus—1) Fixation cross 2)Cue inside or outside receptive field 3)Depress lever 4)Two additional distractor dots appear—one inside or one outside RF 5)All dots start moving 6) After a random period dots change speed 7)Monkey releases lever Responses with two stimuli inside the receptive field. The histograms show the responses of an MST neuron during experiment 2.?The sketches above the histograms represent the movement of the three dots presented, and the dashed ellipses denote the target stimulus in the respective trials. The left two histograms show responses while the animal attended to either the left or the right dot in th