太子健对哮喘豚鼠白细胞介素-5P-选择素的影响pdf.PDFVIP

山西医药杂志2004 年7 月第33 卷第7 期　Shanx i M ed J , July 2004, V ol 33, N o . 7 565 太子健Ⅱ对哮喘豚鼠白细胞介素-5 P -选择素的影响 厦门大学海外教育学院( 36 1005) 　赵育芳 浙 江 中 医 学 院　　　　　周大兴　俞景茂 ( IL ) -5P - 5 , 4 15 d , , , , , 3 , , 15 dIL -5 - -5-, P I L P , ; ; ; 5; P Study on effect of taizijian on interleukin-5 and P-selectin of asthmatic guinea pigsZH A O Y u -f a ng * , ZH O U D a-x ing , Y U J ing -m ao . * Ov e r seas E d uc tion Colleg e, X ia men Un iv e rsity , F u ia n 361005, China -5 - Abstract Objective I nv estig ating the eff ect o f taizi ian o n inter leukin and P selectin in bloo d o f . 5 . asthmat ic g uinea pigs Methods Fo rt y g uinea pig s w er e r ando mly divided int o g ro ups A fter having been sensitized w ith eg g albumin , guinea pig s w er e induced to suff er ast hm atic at tack repeatedly w ith egg albumin in m odel gr o up , dexam ethaso ne ( DX M ) g ro up , t aizi ian lar ge do se g r oup and small dose g ro up . N or mal gr oup r eceiv ed physio lo gical saline. A t the sam e time, g uinea pig s w ere tr eated w ith phy sio lo gical saline in no rmal gr oup and mo del gr oup , and those w er e t reat ed respect ively w ith DXM , taizi iam lar ge dose a nd small dose in the 15 . -5 - . o ther three g ro up s for days Results T aizi ian decr easd inter leukin and P selectin in bloo d Conclusion , . T aizi ian can r elieve t he chr onic aller gic air w ay inflammatio n and sto p children s asthma recur rence