DNA-CTMA_Initial_Project_Presentation_DNA__初稿.ppt

Biopolymer Electronics NI, XIAOHAN Electrical Engineering Electronics Supervisor: Dr. H. van Zalinge University of Liverpool Agenda What is DNA? Why DNA electronics? DNA/CTMA – What is CTMA? DNA/CTMA current research DNA/CTMA compound / solution preparation Device fabrication and measurement set-up Device characterization Project timeline / Gantt chart Acknowledgements / Questions 2 What is DNA? Biopolymers are polymers produced by living organisms. Deoxyribonucleic acid (DNA) is a class of biopolymer. DNA molecules store the information required to encode the?genetic instructions used in the development and functioning of all known living?organisms.? Figure 1 – Molecular Structure of DNA. 3 Why DNA electronics? Low cost Low temperature fabrication Recyclable Biodegradable Biocompatible High optical transparency (good to fabricate LEDs) Tunable electrical properties (conductivity) 4 DNA-CTMAcurrent research 5 Figure 2 – DNA/CTMA BioFET and output characteristics (a), and transfer characteristics (b). Figure 3 – Organic LED (a) light intensity versus BioLED (b). DNA-CTMAWhat is CTMA? 6 Figure 4 – Salmon DNA to DNA/CTMA solution processing flow diagram. DNA films … … are water sensitive. … have poor mechanical strength. … are not compatible with techniques used in polymer based devices. CTMA (detergent) + DNA DNA/CTMA Add CTMA Figure 5 – Chemical reaction to obtain DNA/CTMA. DNA-CTMA compound / solution preparation DI H2O DI H2O Mix at 100rpm for 24h Dissolve DNA in H2O Dissolve CTMA in H2O CTMA DNA Add DNA drop-wise to CTMA. Mechanically stirred for 24h to fully react. DNA- CTMA Vacuum filter DNA/CTMA to remove the water. Dry in the oven at 40 degrees for 24h. Collect from the filter paper, weight and dissolve in 1-butanol. D/C in 1-butanol Figure 6 – DNA/CTMA compound and solution preparation flow diagram. Figure 7 – DNA/CTMA crystals for two different DNA purities. 7 Device fabrication measurement set-