艾迪注射液联合鸦胆子油乳剂腹腔内注射治疗肝癌恶性腹腔积液临床分析-徐芳.pdfVIP

S rai Pharmaceu ical Journal Vol 23 No.5 20 11 徐　芳,徐　磊, 黎红光, 钱俊峰( 323000 ) :　观察艾迪注射液联合鸦胆子油乳剂腹腔内注射治疗肝癌 性腹腔积液的疗效。　将56 例肝癌 性腹腔积液患者随机分为 两组, 艾迪联合鸦胆子油乳剂治疗组和5-氟尿嘧啶(5-F U )对照组, 艾迪联合鸦胆子油乳剂治疗组每周一次腹腔内注射, 对照组采用5-氟尿嘧啶 (5-F U )腹腔内注射,每周一次。两组均最多不超过4 次, 观察疗效及毒副反应。 　艾迪联合鸦胆子油乳剂治疗组总有效率高于对照组, 副 作用发生率低于对照组, 差异均有统计学意义(P0.05)。 　艾迪联合鸦胆子油乳剂治疗肝癌 性腹腔积液疗效好、副作用轻, 患者易于 接受。 :艾迪注射液;鸦胆子油乳剂;肝癌 性腹腔积液 :R969.4　:B 　:1006-3765(20 11)-05-0083-03 Treatment of AiDi injectioncombinedwithbruceajavanice oil emulsion in liver cancer with malignant peritoneal effusion XU Fang,XULei, LI Hong-guang, QIA Jun-feng(Lishui People′s Hospital,Zhejiang 323000,China) ABSTRACT:OBJECTIVE　T o inves iga e he efec of AiDi combined w i h Brucea javanice oil emulsio n in Liver Cancer wi h Malignan peri oneal eff usio n.METHODS　Fif y-six cases wi h L iver Cancer w i h M alig nan peri- oneal eff usion were divided in o w o equal g roups randomly, he con rol group (CG )rea ed w i h 5-F U and ex peri- men al g roup (EG )rea ed wi h A iDi combined Brucea javanice oil emulsion.Bo h CG and EG w ere injec ed once a w eek,no mo re han 4 weeks, o s udy he effec and side effec .RESULTS　T he ef fec ive ra e of EG w as s a is i- cally hig her and he ra e of side eff ec of EC w as s a is ically low er han CG (P0.05 ).CONCLUSION 　I is of higher ef fec , lower side effec and accep abili y for AiDi combined w i h Brucea javanice oil emulsion o rea pleu - ral ef usion of lung adenocarcinoma. AiDi injec ion;Brucea javanice oil emulsion;M alig nan peri oneal effusion KEY WORDS: 　　, 、 , 、、, 、、、。 , 、、、、, , 。 , , 1 , , 、、 。。2 8 , 18 、 , 10 , 55.4 。 28 , 20 、8 , , ; 53.5 。 ( , 。 。)、、, , , , , 、。 KPS ≥50 , ≥3