抗生素的选择与使用（英文PPT）Antibiotic Selection UsePPT.pptVIP

Finding Sick Cattle … Number one rule: ...Have plenty of timeearly every morning........If the temperature is going to be over 70-80 F that day ...... Be finished by 10AM RELOOK AT CATTLE OFTEN how to select a proper antibiotic for different diseases … will focus on BRD Pneumonia … Ab penetration not as much of a problem early as late Bugs that live in cells … need Ab that crosses cell walls Animal’s that are over whelmed can’t help the drug by fighting back … cidal Ab may be better than static Ab Can’t defend the use of Pen G (especially LA Pen) Sulfa in BRD Rx programs CAUTION – Generics … AVOID Bathtub mixes Neomycin Gentamicin … violate BQA reason how to know when to switch 1st … and very important … assess the “stress” effect of the Ab gut fill, soreness, tissue temp, etc don’t switch because of stress effect Monitor animal NOT temp!!! Don’t let the thermometer do your thinking Use temp to confirm your visual assessment Give the Ab 48 hours … @ MIC 90 which antibiotic would make a better choice when you need to switch … poor response Re-check the diagnosis … evaluate the treatment extras being used Use previous lab work … animals that die may be the most valuable If the infection is winning … get meaner Cidal Ab KILL bugs … good selection Ab that penetrate … good selection Ab that minimizes stress effect … may be good Have faith in the treatment plan … stick to it ! Letting go Giving up on a sick animal that has failed to recover is one of the toughest things we ask our treatment crew to do. Medications given to sick cattle that repeatedly fail to respond are extremely expensive. Recognizing when it is time to stop therapy is tough, but simple rules for when to stop must be developed and enforced. Letting go Total cost of therapy may be a good guideline, but should be included with decisions based on the number of therapy days. Management should evaluate continue therapy on all sick cattle that f