聚焦超声与射频消融联合糠酸莫米松治疗持续性变应性鼻炎的疗效研究.docVIP

精品论文 参考文献 聚焦超声与射频消融联合糠酸莫米松治疗持续性变应性鼻炎的疗效研究 杜经纬1 刘文祥2 彭 涛1 李红光1 冯 俊1 苏莉莎1 　　1.南充市中心医院耳鼻咽喉科 四川南充 637000； 　　2.南充市第五人民医院五官科医院 四川南充 637100 　　【摘 要】目的：研究聚焦超声与射频消融联合糠酸莫米松治疗持续性变应性鼻炎（Perennial allergic rhinitis，PAR）的疗效。方法：将142例病人随机分为2组，聚焦超声治疗组（A组）72例，等离子射频消融组（B组）70例，分别在鼻内镜下行聚焦超声与射频消融治疗，术后应用糠酸莫米松鼻喷雾剂喷鼻1月，治疗后随访1年，用计分法进行疗效评价。结果：总有效率分别为：1月：A组97.2%，B组97.1%(Pgt;0.05)；6月：A组90.3%，B组87.1%( P gt;0.05)；12月：A组83.3%，B组77.1%( P gt;0.05) 。两组治疗后症状评分比较，疗效相当，无统计学差异(P gt;0.05)；治疗后喷嚏、清涕、鼻痒症状评分比较，A组优于B组，差异有显著性(P P lt;0.05)，但鼻塞评分比较，B组优于A组，差异有显著性(P lt;0.05)。结论：聚焦超声与射频消融联合糠酸莫米松治疗PAR，疗效相当，前者改善喷嚏、清涕、鼻痒症状优于后者，但改善鼻塞症状不如后者。聚焦超声联合糠酸莫米松治疗PAR, 微创、安全性高、疗效确实可靠，值得推广。 　　【关键词】变应性鼻炎；持续性；聚焦超声；射频消融 　　【中图分类号】R454 【文献标识码】B 【文章编号】1674-8999（2015）8-0241-02 　　Curative effect study of treatment with focused ultrasound and radiofrequency ablation combined with mometasone furoate for perennial allergic rhinitis 　　DU Jing-wei 1, LIU Wen-xiang 2, PENG Tao 1, LI Hong-guang 1, FENG Jun 1, SU Li-sha 1 　　(1.Department of Otolaryngology, Nanchong Central Hospital, Nanchong 637000, Sichuan; 2. ENT Hospital , Nanchong Fifth Peoples Hospital,Nanchong 637000, Sichuan) 　　【Abstract】Objective To study curative effect in the treatment of Perennial allergic rhinitis for focused ultrasound and radiofrequency ablation combined with mometasone furoate. Methods 142 patients were randomly divided into 2 groups, focused ultrasound treatment group (A group) 72 cases, radiofrequency ablation group (group B) 70 cases, sespectively in focused ultrasound and radiofrequency ablation therapy under nasal endoscopy, after operation, spraying Mometasone Furoate Nasal Spray for 1 month, followed up for 1 year after treatment, evaluation of curative effect with scoring method. Results The total effectiveness respectively is: 1 month: A group 97.2%, B group 97.1% (P gt;0.05); 6 months: A group 90.3%, B group 87.1% (P gt;0.05); 12 months: A group 83.3%, B group 77.1% (P gt;0.05). Symptom scores to compare the two groups after treatment, the