氟马西尼与纳洛酮在治疗苯二氮卓类药物中毒患者中的应分析.docVIP

精品论文 参考文献 氟马西尼与纳洛酮在治疗苯二氮卓类药物中毒患者中的应分析 赵国红 　　（双江自治县人民医院门急诊科 云南 临沧 677300） 　　【摘要】 目的：研究和探讨氟马西尼与纳洛酮在治疗苯二氮卓类药物中毒患者中的应用。方法：将我院急诊科2013.4～2015.6期间收治的苯二氮卓类药物中毒的患者，随机抽取74例，做为本次研究对象，按随机双盲法分为观察组和对照组，观察组37例，采用氟马西尼联合纳洛酮对其进行治疗，对照组37例，采用纳洛酮对其进行治疗，采用格拉斯哥昏迷评分量表（glasgow comascale.GCS）对两组患者治疗前后的GCS进行比较，及治疗后观察两组患者的临床催醒效果与不良反应。结果：观察组治疗后的GCS得分为（13.6plusmn;2.1）明显高于对照组的（8.9plusmn;2.7），有统计学意义（P＜0.05），且观察组的清醒时间及治愈率分别为（3.85plusmn;1.1）、29（78.3）明???优于对照组的（8.87plusmn;2.6）、20（54.0），有统计学差异（P＜0.05）。结论： 氟马西尼联合纳洛酮治疗苯二氮卓类药物中毒，疗效显著，能有效的缩短患者的清醒时间，值得在临床上进行推广及应用。 　　【关键词】 氟马西尼；纳洛酮；苯二氮卓类；药物中毒 　　【中图分类号】R97 【文献标识码】A 【文章编号】2095-1752（2016）03-0024-02 　　Flumazenil and naloxone in the treatment of patients in the application of two benzodiazepines poisoning Zhao Guohong. 　　Emergency Department, The Peoples Hospital of Shuangjiang Autonomous County,Yunnan Lincang 677300,China 　　【Abstract】Objective To investigate flumazenil and naloxone in the treatment of patients with two benzodiazepines poisoning. Methods In our hospital emergency department 2013.4~2015.6 admitted during the period of the benzodiazepine Zhuo drugs poisoning patients were randomly selected from 74 cases, do as the research object, by the method of randomized, double-blind divided into the observation group and the control group, observation group (37 cases), using flumazenil and naloxone for the treatment, control group (37 cases) and by naloxone for the treatment and the Glasgow coma score table (Glasgow comascale.GCS) before and after the treatment, the patients in the two groups of GCs were compared, and after treatment observed two groups of patients with clinical reminder wake effect and adverse reaction of. Results The GCS score of the observation group was significantly higher than that of the control group (2.7 2.1), with statistical significance (P lt; 0.05), and the recovery time and the cure rate of the observation group were (3.85 1.1), 29 (78.3) were significantly better than the con