慢性阻塞性肺疾病患者低氧血症与左心功能的关系.docVIP

精品论文 参考文献 慢性阻塞性肺疾病患者低氧血症与左心功能的关系 胡小容 　　(四川省成都市双流县第一人民医院呼吸内科 四川 成都 610200) 　　【摘要】 目的：探讨慢性阻塞性肺疾病（COPD）患者低氧血症与左心功能的关系。方法：对48例年龄40～80岁的诊断慢性阻塞性肺疾病的患者行血气分析及超声心动图检查，根据氧分压分为呼吸衰竭组和无呼吸衰竭组，与18例肺功能正常的患者比较左心室功能功能及结构即舒张早期血流速度峰值/舒张晚期血流速度峰值（E/A）、E峰速时间（EDT）、短缩分数（FS%）、左室射血分数（LVEF%）、左心室舒张末内径（LVEDD）的关系。结果：①无呼吸衰竭组患者E/A值与对照组相比显著降低，差异有统计学意义（P＜0.05）；EDT相比显著延长，差异有统计学意义（P＜0.05）；LVEFF%、FS%及LVEDD相比差异无统计学意义。②呼吸衰竭组患者E/A值与对照组及无呼吸衰竭组相比显著降低，差异有统计学意义，分别为P＜0.01及P＜0.05；EDT相比显著延长，差异有统计学意义（P＜0.05）；LVEFF%、FS%及LVEDD相比差异无统计学意义。③三组E/A值与氧分压值呈正相关（r=0.79,P＜0.01）。结论：低氧血症是引起COPD患者左心室舒张功能下降的重要原因，并且与缺氧程度成正相关。低氧程度的加重对LVEF%无影响。 　　【关键词】 慢性阻塞性肺疾病；低氧血症；左心功能 　　【中图分类号】R56 【文献标识码】A 【文章编号】2095-1752（2016）04-0023-02 　　Relationship between hypoxemia and left ventricular function in patients with chronic obstructive pulmonary disease Hu xiaorong. 　　Department of Respiratory Medicine , The First Hospital of Shuangliu Country, Sichuan Province, Chengdu 610200,Chian 　　【Abstract】Objective To investigate the relationship between hypoxemia and left ventricular function in patients with chronic obstructive pulmonary disease(COPD).Methods Measured blood gas analysis in 48 COPD patients who were 40 to 80 years of age, these patients were divided into respiratory failure group and non-respiratory failure group according to partial pressure of oxygen, at the same time measured left ventricular function, that is the ratio of early mitral peak flow to atria mitral peak flow (E/A),E deceleration time (EDT),Fractional shortening (FS%), left ventricular ejection fraction (LVEF%), left ventricular end diastolic diameter (LVEDD) by echocardiography in these patients. And compared with the left ventricular function and structure of 18 people with normal lung function.Results ①Non-respiratory failure group patients E/A value were significantly lower than normal control group, the difference was statistically significant (P＜0.05),EDT was significantly prolonged ,the difference was statistically signifi