愈喘至圣膏的制备及临床应用.docVIP

精品论文 参考文献 愈喘至圣膏的制备及临床应用 柳冬梅 殷生楠 　　南京中医药大学泰州附属医院 江苏泰州 225300 　　【摘 要】目的：制备愈喘至圣膏，并观察其对“喘证”“肺胀”“痰饮”患者的临床疗效。方法：根据药典膏剂制备规范，将我院临床治疗咳喘的协定处方愈喘汤制备成膏剂（制备愈喘至圣膏，治疗组），与传统汤剂（对照组）进行疗效对比观察。结果：膏剂质量稳定，疗效确切；治疗组总有效率为90.6%，对照组的84.3%，两组相比差异无统计学意义。结论：该膏剂疗效显著，制备方法合理，适合制备为成方在临床推广应用。 　　【关键词】 愈喘至圣膏；制备；质量控制；疗效 　　【中图分类号】R972.12 【文献标识码】B 【文章编号】1674-8999（2015）8-0206-02 　　More breath of the Holy of Holies cream Preparation and Clinical Application 　　Yin Shengnan, Liu Dongmei 　　(Nanjing University of Chinese Medicine Taizhou Hospital Affiliated to JiangsuTaizhou 225300) 　　【Abstract】Purpose：Preparation of yuchuanzhishengao ointment and observing their clinical efficacy in patients with asthma, Lung inflation and phlegm. Method：According to agreement of ointment preparation methods in Chinese Pharmacopoeia 2010, we change our treatment of patients with cough and asthma from yuchuan soup (control group) to yuchuanzhishengao ointment (treatment group) in Peoples Hospital of Taizhou City, at the same time, observe and compare their clinical efficacy.Result：Comparing with yuchuan soup, yuchuanzhishengao ointment quality is more stable and effect is more curative. The total effective rate was 90.6% in the treatment group and 84.3% in the control group, no significant difference between the two groups. Conclusion：yuchuanzhishengao ointment with curative effect and simple preparation method, so itrsquo;s suitable for preparation of yuchuanzhishengao ointment for clinical application. 　　【Key words】yuchuanzhishengao ointment；Preparation method；Quality control；Clinical efficacy 　　膏方在我国的应用由来已久，为中药五大剂型之一，近几年，膏方的服用已经被越来越多的患者所推崇，随着每年泰州地区膏方节的召开，我院膏方的产量迅速增加，2008-2014年每年均有60%以上的增幅。近年来我院将愈喘至圣膏作为协定处方，进行批量生产，方便患者服用。通过临床实践验证，取得显著疗效，现报道如下。 　　1 仪器和试药 　　061102多功能提取器（温州鸿驰化工医药设备有限公司）；AEL-200电子分析天平（福州仟度仪器仪表有限公司）；ACS-A型电子计重秤（上海友声卫器有限公司）；AIRTECH无菌操作台（苏净集团安泰公司）；BD/BC-358B冷藏柜（星星集团有限公司）。路党参、炙黄芪、怀山药、炒白术、胡桃肉、熟地黄、制黄精、全当归、南沙参、云茯苓、炙紫苑、款冬花、炙百部、紫苏子、法半夏、白芥子、大贝母、桃仁泥、苦杏仁、干姜、广陈皮、炙麻黄、五味子、沉香、白果、炙甘草、紫河车、蛤蚧饮片均由泰州市仁济医药公司提供（批号分别为：201309