六味地黄丸联合消渴丸治疗气阴两虚2型糖尿病的临床研究.PDFVIP

Drug Evaluation Research 第 39 卷 第 3 期 2016 年 6 月 • 445 • 六味地黄丸联合消渴丸治疗气阴两虚 2 型糖尿病的临床研究 柴彦军 志丹县人民医院中医内科，陕西 延安 717500 摘 要：目的 探讨消渴丸联合六味地黄丸治疗气阴两虚 2 型糖尿病的临床疗效。方法 选择 2013 年 5 月—2015 年 5 月在 志丹县人民医院进行诊治的气阴两虚 2 型糖尿病患者 100 例，随机分为观察组与对照组，每组各 50 例。对照组采用消渴丸 治疗，观察组在对照组基础上加用六味地黄丸治疗，比较两组的治疗效果。结果 观察组的总有效率为 84.00%，明显高于 对照组 68.00% （P ＜0.05 ）；两组患者治疗后的空腹血糖和餐后2 h 血糖水平均明显低于治疗前（P ＜0.05 ），治疗后观察组的 餐后 2 h 血糖水平明显低于对照组（P ＜0.05 ）；观察组的气短懒言、惓息乏力、盗汗、自汗、口渴喜饮、五心烦热及便秘症 状的治疗有效率明显高于对照组（P ＜0.05 ）。结论 六味地黄丸联合消渴丸治疗气阴两虚 2 型糖尿病疗效显著，值得临床应 用推广。 关键词：消渴丸；六味地黄丸；气阴两虚；2 型糖尿病 中图分类号：R969.4 文献标志码：A 文章编号：1674 - 6376 (2016) 03 - 0445 - 04 DOI: 10.7501/j.issn.1674-6376.2016.03.024 Clinical study on Xiaoke Pill combined with Liuwei Dihuang Pill in treatment of type 2 diabetes mellitus with Qi and Yin deficiency CHAI Yan-jun Department of traditional Chinese internal medicine, Zhidan People ’s Hospital, Zhidan 717500, China Abstract: Objective To investigate the clinical effect of Xiaoke Pill combined with Liuwei Dihuang Pill in treating type 2 diabetes mellitus with Qi and Yin deficiency. Methods Totally 100 cases of patients with type 2 diabetes mellitus with Qi and Yin deficiency who were treated in Zhidan People’s Hospital from May 2013 to May 2015 were selected and randomly divided into two groups, 50 cases in each group. The patients in observation group were treated with Xiaoke Pill combined with Liuwei Dihuang Pill, the patients in control group were treated with Xiaoke Pill, and the therapeutic effects of two groups were compared. Results The total effective rate in the observation group was 84.00%, significantly higher than that of 68.00% in the control group (P 0.05). Fasting blood glucose and postprandial 2 h blood glucose levels in the two groups were all significantly decreased after treatment (P 0.05), the postplandial 2 h blood glucose level in t