产前催产素不同使用剂量与新生儿黄疸的关系研究.docVIP

精品论文 参考文献 产前催产素不同使用剂量与新生儿黄疸的关系研究 （北京市通州区妇幼保健院儿科，邮编101100） 【摘要】 目的 探讨产前应用不同剂量催产素与新生儿黄疸的关系。方法 选择足月孕龄且具备阴道试产条件与催产素引产指征的孕妇196例为观察组，分为A组(n=98)与B组(n=98)，A组给予10U催产素，B组给予15U催产素，另取100例未使用催产素的足月产妇为对照组，对比三组患者血清总胆汁酸（TBA）与胆红素。结果 A组TBA与对照组比较差异无统计学意义（Pgt;0.05）,B组显著高于对照组（Plt;0.05）。A组新生儿胆红素与对照组各期比较差异无统计学意义（Pgt;0.05），B组第3天、第4天与对照组比较显著增高（Plt;0.05）。结论 产前应用催产素剂量越高新生儿黄疸几率越大，应严格把握催产素用量，以保证母婴安全。 【关键词】 催产素，新生儿黄疸，血清总胆汁酸 Analysis of the Relationship between Different Dose of Oxytocin with Jaundice of the Newborn 【Abstract】Objective To discuss the relationship between different dose of oxytocin with Jaundice of the newborn. Methods 196 pregnant women with full-term gestational age and vaginal delivery conditions, oxytocin induction of the indications were divided into the observation group, and 98 cases were given 10U oxytocin(observation group A), 98 cases were given 15U oxytocin(observation group B), and 100 pregnant women with full-term gestational age were divided into the control group, then TBA and bilirubin were contrasted between the newborn of the three groups. Results There was no significantly difference in TBA and bilirubin between observation group A and the control group postpartum (Pgt;0.05), but TBA in observation group B was significantly higher than the control group(Plt;0.05); bilirubin in observation group A was significantly higher than the control group 3,4 days postpartum (Plt;0.05). Conclusion The incidence of neonatal jaundice is higher when prenatal use of oxytocin dose more, so we should strictly grasp the oxytocin dosage to ensure maternal and child safety. 【Key Words】Oxytocin; Dose; Neonatal Jaundice 本研究通过检测新生儿血清胆红素（TBA），旨在探讨催产素的合理使用量与时间，现报道如下。 1 资料与方法 1.1 一般资料 选择我院产科2008年1月-2013年9月出生的足月儿296例，男150例，女146例，胎龄38+1-41+2周，平均（39plusmn;2.2）周。出生体重2521-4000g，平均（3100plusmn;234）g。出生后一分钟断脐，Apgar计分均超过8分[1]。排除新生儿溶血、颅内血肿、红细胞增多症、胎粪排出延迟及第二产程延长等疾病。开奶时间均在6小时内，孕妇排除合并妊娠合并症，分娩时未使用镇静药物。所有新生儿为阴道生产，其中196例孕妇生产时使用催产素为观察组，按照使用催产素用量分为两组，A组98例使用10U催产素，B组98例使用15U；另外100例孕妇生产未使用催产