氯氮平片（Clozapine Tablets）.docVIP

氯氮平片（Clozapine Tablets） Clozapine Tablets.Txt is in a bad mood today. I have only four words to say. Include this sentence and the preceding two sentences. My word is finished, to deal with evil people, will be more vicious than him; to deal with despicable people, it is more despicable than he, no Valentines taste, where the human touch, what the whole death of you, my love. No change, said the cashier. Two plastic bags for you.! Clozapine Tablets Name used before English name CLOZAPINE TABLETS Pinyin name LUDANPIN PIAN Drug category antipsychotic drugs Character of this product is light yellow. The pharmacology and toxicology of this strain are two benzene two nitrogen compounds antipsychotic drugs. The 5- in brain serotonin (5-HT2A) receptor and dopamine (DA1) receptor blockade strong on dopamine (DA4) receptor and inhibition of dopamine (DA2) receptor blocking effect is weak, in addition to anti choline (M1), anti histamine (H1) and anti - adrenaline receptor? Effect of rare extrapyramidal reactions, generally do not cause the blood prolactin. It can directly inhibit the ascending activation system of brain stem reticular formation, and has a powerful sedative and hypnotic effect. The pharmacokinetics of oral absorption of fast food, no influence on the rate and extent of absorption, absorption quickly after widely distributed to various organizations, the bioavailability of individual differences, the average is about 50%~60%, the liver first pass effect. The peak concentration of plasma reached 3.2 hours (1~4 hours), and the half-life (t1/2) was 9 hours (3.6~14.3 hours), the apparent volume of distribution (Vd) 4.04~13.78L/kg, and the rate of tissue binding was high. After liver metabolism, 80% appeared in urine and feces in the form of metabolites, and the main metabolites were N-, demethylation, clozapine, N- oxide of clozapine, etc.. At the same dose and weight, the serum concentration of female patients was significantly higher than that of male patients.