cross-lineage influenza b and heterologous influenza a antibody responses in vaccinated mice immunologic interactions and byamagata dominancecross-lineage乙型流感和异种的流感接种小鼠的抗体反应免疫交互和byamagata主导地位.pdfVIP

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cross-lineage influenza b and heterologous influenza a antibody responses in vaccinated mice immunologic interactions and byamagata dominancecross-lineage乙型流感和异种的流感接种小鼠的抗体反应免疫交互和byamagata主导地位.pdf

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cross-lineage influenza b and heterologous influenza a antibody responses in vaccinated mice immunologic interactions and byamagata dominancecross-lineage乙型流感和异种的流感接种小鼠的抗体反应免疫交互和byamagata主导地位

Cross-Lineage Influenza B and Heterologous Influenza A Antibody Responses in Vaccinated Mice: Immunologic Interactions and B/Yamagata Dominance Danuta M. Skowronski1,2*, Marie-Eve Hamelin3,4, Naveed Z. Janjua1,2, Gaston De Serres5,6, 1,7 ´ 4 4 3,4 Jennifer L. Gardy , Chantal Rheaume , Xavier Bouhy , Guy Boivin 1 Communicable Disease Prevention and Control Services, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada, 2 School of Population and ´ ´ Public Health, University of British Columbia, Vancouver, British Columbia, Canada, 3 Department of Microbiology and Immunology, Laval University, Quebec, Quebec, ´ ´ ´ Canada, 4 Department of Micrbiology and Immunology, Centre Hospitalier Universitaire de Quebec, Quebec, Quebec, Canada, 5 Department of Social and Preventive ´ ´ ´ ´ Medicine, Faculty of Medicine, Laval University, Quebec, Quebec, Canada, 6 Direction of Biological and Occupational Risks, Institut national de sante publique du Quebec, ´ Quebec, Canada, 7 Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada Abstract The annually reformulated trivalent inactivated influenza vaccine (TIV) includes both influenza A/subtypes (H3N2 and H1N1) but only one of two influenza B/lineages (Yamagata or Victoria). In a recent series of