the brain’s dorsal route for speech represents word meaning evidence from gesture大脑的背路线从手势演讲代表词义的证据.pdfVIP

The Brain’s Dorsal Route for Speech Represents Word Meaning: Evidence from Gesture 1 2 3 4 Goulven Josse *, Sabine Joseph , Eric Bertasi , Anne-Lise Giraud ¨ ´ ` ˆ ´ ˆ ` 1 Institut du Cerveau et de la Moelle epiniere, Hopital de la Pitie-Salpetriere, Paris, France, 2 Cognitive Neurology Group, Institute of Cognitive Neuroscience, University ¨ ´ College London, London, United Kingdom, 3 Centre de NeuroImagerie de Recherche (CENIR), Centre de Recherche de l’Institut du Cerveau et de la Moelle, Universite ˆ ´ ˆ ` Pierre et Marie Curie - INSERM UMRS 975 - CNRS UMR 7225, Hopital de la Pitie-Salpetriere, Paris, France, 4 Laboratoire de Neurosciences Cognitives - INSERM U960, ´ ´ Departement d’Etudes Cognitives, Ecole Normale Superieure, Paris, France Abstract The dual-route model of speech processing includes a dorsal stream that maps auditory to motor features at the sublexical level rather than at the lexico-semantic level. However, the literature on gesture is an invitation to revise this model because it suggests that the premotor cortex of the dorsal route is a major site of lexico-semantic interaction. Here we investigated lexico-semantic mapping using word-gesture pairs that were either congruent or incongruent. Using fMRI-adaptation in 28 subjects, we found that temporo-parietal and premotor activity during auditory processing of single action words was modulated by the prior audiovisual