systematic review of worldwide variations of the prevalence of wheezing symptoms in children系统回顾全球儿童喘息症状的患病率的变化.pdfVIP

Environmental Health BioMed Central Review Open Access Systematic review of worldwide variations of the prevalence of wheezing symptoms in children 1,2 2 2 Swatee P Patel , Marjo-Riitta Järvelin and Mark P Little* Address: 1School of Health and Social Care, the University of Greenwich, Southwood Site, Avery Hill Road, London SE9 2UG, UK and 2Department of Epidemiology and Public Health, Imperial College Faculty of Medicine, Norfolk Place, London W2 1PG, UK Email: Swatee P Patel - s.p.patel@gre.ac.uk; Marjo-Riitta Järvelin - m.jarvelin@imperial.ac.uk; Mark P Little* - mark.little@imperial.ac.uk * Corresponding author Published: 10 November 2008 Received: 18 February 2008 Accepted: 10 November 2008 Environmental Health 2008, 7:57 doi:10.1186/1476-069X-7-57 This article is available from: /content/7/1/57 © 2008 Patel et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Considerable variation in the prevalence of childhood asthma and its symptoms (wheezing) has been observed in previous studies and there is evidence that the prevalence has been increasing over time. Methods: We have systematically reviewed the reported prevalence and time tre