有哪些信誉好的足球投注网站an observational cohort comparison of facilitators of retention in care and adherence to anti-eetroviral therapy at an hiv treatment center in kenya保留的助理员观察队列比较关心和坚持anti-eetroviral疗法在肯尼亚的艾滋病毒治疗中心.pdfVIP
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an observational cohort comparison of facilitators of retention in care and adherence to anti-eetroviral therapy at an hiv treatment center in kenya保留的助理员观察队列比较关心和坚持anti-eetroviral疗法在肯尼亚的艾滋病毒治疗中心
An Observational Cohort Comparison of Facilitators of
Retention in Care and Adherence to Anti-Eetroviral
Therapy at an HIV Treatment Center in Kenya
1,2 2 3,4 1 4
Loice Achieng , Helen Musangi , Sharon Ong’uti , Edwin Ombegoh , LeeAnn Bryant , Jonathan
4 1,5 4
Mwiindi , Nathaniel Smith , Philip Keiser *
1 A.I.C. Kijabe Hospital, Kijabe, Kenya, 2 University of Nairobi, Nairobi, Kenya, 3 Johns Hopkins University, Baltimore, Maryland, United States of America, 4 University of
Texas Medical Branch, Galveston, Texas, United States of America, 5 Arkansas Department of Health, Little Rock, Arkansas, United States of America
Abstract
Background: Most HIV treatment programs in resource-limited settings utilize multiple facilitators of adherence and
retention in care but there is little data on the efficacy of these methods. We performed an observational cohort analysis of
a treatment program in Kenya to assess which program components promote adherence and retention in HIV care in East
Africa.
Methods: Patients initiating ART at A.I.C. Kijabe Hospital were prospectively enrolled in an observational study. Kijabe has an
intensive program to promote adherence and retention in care during the first 6 months of ART that incorporates the
following facilitators: home visits by community health workers, community based support groups, pharmacy counseling,
and unannounced pill counts by clinicians. The primary endpoint was time to treatment failure, defined as a detectable HIV-
1 viral load; discontinuation of ART; death; or loss to follow-up. Time to treatment failure for each facilitator was calculated
using Kaplan-
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