有哪些信誉好的足球投注网站a new method for morphometric analysis of tissue distribution of mobile cells in relation to immobile tissue structures新方法的形态学分析的组织分布移动与固定组织的细胞结构.pdfVIP
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a new method for morphometric analysis of tissue distribution of mobile cells in relation to immobile tissue structures新方法的形态学分析的组织分布移动与固定组织的细胞结构
A New Method for Morphometric Analysis of Tissue
Distribution of Mobile Cells in Relation to Immobile
Tissue Structures
1¤ 2 1 3 4
Liudmila Nikitina , Helmut Ahammer , Astrid Blaschitz , Angela Gismondi , Andreas Glasner ,
5 1 1
Michael G. Schimek , Gottfried Dohr , Peter Sedlmayr *
1 Institute of Cell Biology, Histology and Embryology, Medical University of Graz, Graz, Austria, 2 Institute of Biophysics, Medical University of Graz, Graz, Austria,
3 Department of Experimental Medicine, University of Rome ‘‘La Sapienza’’, Rome, Italy, 4 Gynecological practice, Seiersberg, Austria, 5 Institute for Medical Informatics,
Statistics and Documentation, Medical University of Graz, Graz, Austria
Abstract
The distribution of cells in stained tissue sections provides information that may be analyzed by means of morphometric
computation. We developed an algorithm for automated analysis for the purpose of answering questions pertaining to the
relative densities of wandering cells in the vicinity of comparatively immobile tissue structures such as vessels or tumors. As
an example, we present the analysis of distribution of CD56-positive cells and of CXCR3-positive cells (relative densities of
peri-vascular versus non-vascular cell populations) in relation to the endothelium of capillaries and venules of human
parietal decidua tissue of first trimester pregnancy. In addition, the distibution of CD56-positive cells (mostly uterine NK
cells) in relation to spiral arteries is analyzed. The image analysis is based on microphotographs of two-color
immunohistological stainings. Discrete distances (10–50 mm)
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