有哪些信誉好的足球投注网站a mutual support mechanism through intercellular movement of caprice and glabra3 can pattern the arabidopsis root epidermis相互支持机制通过胞间运动的任性和glabra3模式拟南芥根表皮.pdfVIP
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a mutual support mechanism through intercellular movement of caprice and glabra3 can pattern the arabidopsis root epidermis相互支持机制通过胞间运动的任性和glabra3模式拟南芥根表皮
PLoS BIOLOGY
A Mutual Support Mechanism through
Intercellular Movement of CAPRICE and
GLABRA3 Can Pattern the Arabidopsis
Root Epidermis
1 2 3 3 2 4,5*
Natasha Saint Savage , Tom Walker , Yana Wieckowski , John Schiefelbein , Liam Dolan , Nicholas A. M. Monk
1 Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, United Kingdom, 2 Department of Cell and Developmental Biology, John Innes
Centre, Norwich, United Kingdom, 3 Department of Molecular, Cell, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America,
4 Division of Applied Mathematics, School of Mathematical Sciences, University of Nottingham, Nottingham, United Kingdom, 5 Centre for Plant Integrative Biology, School
of Biosciences, University of Nottingham, Loughborough, United Kingdom
The patterning of the Arabidopsis root epidermis depends on a genetic regulatory network that operates both within
and between cells. Genetic studies have identified a number of key components of this network, but a clear picture of
the functional logic of the network is lacking. Here, we integrate existing genetic and biochemical data in a
mathematical model that allows us to explore both the sufficiency of known network interactions and the extent to
which additional assumptions about the model can account for wild-type and mutant data. Our model shows that an
existing hypothesis concerning the autoregulation of WEREWOLF does not account fully for the expression patterns of
components of the network. We confirm the lack of WEREWOLF autoregulation experimentally in transgenic plants.
Rather, our modelling suggests that p
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