4-acetoxydolastane diterpene from the brazilian brown alga canistrocarpus cervicornis as antileishmanial agent4-acetoxydolastane二萜从巴西的棕色海藻canistrocarpus cervicornis为antileishmanial的代理.pdfVIP

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4-acetoxydolastane diterpene from the brazilian brown alga canistrocarpus cervicornis as antileishmanial agent4-acetoxydolastane二萜从巴西的棕色海藻canistrocarpus cervicornis为antileishmanial的代理.pdf

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4-acetoxydolastane diterpene from the brazilian brown alga canistrocarpus cervicornis as antileishmanial agent4-acetoxydolastane二萜从巴西的棕色海藻canistrocarpus cervicornis为antileishmanial的代理

Mar. Drugs 2011, 9, 2369-2383; doi:10.3390/md9112369 OPEN ACCESS Marine Drugs ISSN 1660-3397 /journal/marinedrugs Article 4-Acetoxydolastane Diterpene from the Brazilian Brown Alga Canistrocarpus cervicornis as Antileishmanial Agent 1 2 3 Adriana Oliveira dos Santos , Elizandra Aparecida Britta , Everson Miguel Bianco , Tania Ueda-Nakamura 2, Benedito Prado Dias Filho 1,2, Renato Crespo Pereira 4 and Celso Vataru Nakamura 1,2,* 1 Postgraduate Program in Microbiology, State University of Londrina, Highway Celso Garcia Cid, PR 445, Km 380, CEP 86051-990, Londrina, Parana, Brazil; E-Mails: oi_dri@ (A.O.d.S.); bdpfilho@uem.br (B.P.D.F.) 2 Postgraduate Program in Pharmaceutical Sciences, Laboratory of Technological Innovation in the Development of Drugs and Cosmetics, State University of Maringa, Colombo Avenue 5790, CEP 87020-900, Maringa, Parana, Brazil; E-Mails: elizandrabritta@ (E.A.B); tunakamura@uem.br (T.U.-N.) 3 Postgraduate Program in Chemistry, Department of Fundamental Chemistry, Federal University of Pernambuco, CEP 50670-901, Recife, Pernambuco, Brazil; E-Mail: ebianco@ 4 Department of Marine Biology, Federal Fluminense University, PO Box 100644, CEP 24001-970, Niteroi, Rio de Janeiro, Brazil; E-Mail: egbrecp@vm.uff.br * Author to whom correspondence should be addressed; E-Mail: cvnakamura@uem.br; Tel.: +55-44-3011-5012; Fax: +55-44-3011-5046. Received: 14 September 2011; in revised form: 1 October 2011 / Accepted: 18 October 2011