丙种球蛋白联合甲基泼尼松龙治疗重症毛细支气管炎临床研究.docVIP

丙种球蛋白联合甲基泼尼松龙治疗重症毛细支气管炎临床研究[摘要] 目的：探讨人血丙种球蛋白联合甲基泼尼松龙治疗重症毛细支气管炎的临床疗效。方法：将114例重症毛细支气管炎患儿随机分为治疗组及对照组，每组57例，两组患儿均给予吸氧、止咳平喘、抗感染等基础治疗，对照组患儿给予甲基泼尼松龙治疗，治疗组患儿给予甲基泼尼松龙联合丙种球蛋白治疗，治疗1周后观察两组患儿临床疗效。结果：治疗1周后，治疗组临床有效率为91.2%，对照组临床有效率为80.7%，治疗组临床有效率高于对照组，治疗组咳嗽、喘憋、哮鸣音消失及胸部X线好转时间短于对照组，差异具有统计学意义。结论：丙种球蛋白联合甲基泼尼松龙治疗重症毛细支气管炎比单用甲基泼尼松龙治疗更能够有效缓解临床症状，改善临床治疗效果。 [关键词] 丙种球蛋白；甲基泼尼松龙；毛细支气管炎重症；临床分析 [中图分类号] R974[文献标识码]B [文章编号]1674-4721（2011）06（a）-078-02 Clinical analysis of gamma globulin combinated methylprednisolone on severe bronchiolitis TANG Dan1, SU Peiyuan2, LIANG Ping1 1.Department of Pediatrics, the Second Clinical College of Chengdu University of Traditional Chinese Medicine, Sichuan Province, Chengdu 611137, China; 2.Department of Respiration, Children’s Hospital of Chengdu, Sichuan Province, Chengdu 610017, China [Abstract] Objective: To invesitate the clinial effect of gamma globulin combinated methylprednisolone on severe bronchiolitis. Methods: 114 cases of suffering children with severe bronchiolitis were selected and were randomly divided into therapia group and control group, there were 57 cases of suffering children in every group, all suffering children received treated with inhaling oxygen, antitussive and antiasthmatic, anti-infection, suffering children in control group treated with methylprednisolone, suffering children in therapia group treated with globulin combinated methylprednisolone, after one week, clinical curative effect were contrasted between control group and therapia group. Results: One week after treatment, clinical effective power was 91.2% in therapia group and was 80.7% in control group, clinical effective power was higher in therapia group than in control group, time of cough, gasping and rales disappearing was shorter in therapia group than in control group, time of lung X-ray plate improving was shorter in therapia group than in control group. Conclusion: Gamma globulin combinated methylprednisolone can release clinical symptom on severe br