糖尿病治疗药物（Diabetes treatment drugs）.docVIP

糖尿病治疗药物（Diabetes treatment drugs） Clinical application of oral antidiabetic drugs Abstract Objective: to reveal the research progress of oral antidiabetic drugs and to promote its rational use in clinic. Methods: the literatures about oral treatment of type 2 diabetes mellitus in China were analyzed and summarized in recent 3 years. Results: the clinical use of oral anti diabetic drugs with metformin as the drug of choice for most patients with newly diagnosed diabetes, combined with patients and health status, to choose the application of sulfonylurea, # glucosidase inhibitor, thiazolidine ketone, two non sulfonylurea antidiabetic drug (glinides), this 5 kinds of basic drugs for the treatment of type 2 diabetes, and another two dipeptidyl peptidase inhibitor clinical data is less. Conclusion: Patients with diabetes should be rational drug selection according to their own situation, must be on time and quality, adhere to medication, and regularly check the blood sugar, blood ester, liver and kidney function, HbA1c index, in order to instantly adjust drug varieties and dosage, minimize adverse reactions, improve the life quality of patients with diabetes mellitus. Keywords oral antidiabetic drugs; rational use; IDF report from 2010-2030 patients with diabetes worldwide the number will increase from 285 million to 439 million, and in patients with impaired glucose tolerance will increase from 344 million to 472 million [1] this shows that by 2030, the world will have 900 million people suffering from diabetes or diabetes in high-risk status, they risk suffering from cardiovascular disease increased 2-3 times. At present, as the global an epidemic of diabetes on health, social and economic had a devastating impact. Diabetes is a metabolic disease caused by various causes, which is caused by defects in insulin secretion and / or insulin defect caused by chronic hyperglycemia, and carbohydrate, fat and protein metabolism disorders. Its chronic complications mainly includ