糖尿病口服药物的分类、使用（Classification and use of oral drugs for diabetes mellitus）.docVIP

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糖尿病口服药物的分类、使用（Classification and use of oral drugs for diabetes mellitus）.doc

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糖尿病口服药物的分类、使用（Classification and use of oral drugs for diabetes mellitus）

糖尿病口服药物的分类、使用（Classification and use of oral drugs for diabetes mellitus） Classification, use and precautions of oral diabetes drugs 1. Classification and taking method of oral antidiabetic drugs There are many kinds of oral antidiabetic drugs. At present, the clinical common varieties according to the function or function can be divided into insulin secretion, glucose metabolism in promoting agent and surrounding tissue cells inhibit intestinal absorption of glucose alpha glucosidase inhibition, improve insulin sensitivity and bioavailability of insulin sensitizer, a total of 4 major categories. Because of the principle of action, the timing of onset, the route of metabolism, and the time to match the food, the method of administration is as follows: (1) an insulin releasing agent Antidiabetic drugs that promote insulin secretion, including sulfonylurea and non sulfonylureas, two. The sulfonylurea drugs represent: glibenclamide, Gliquidone, glipizide, gliclazide, glipizide XL, Amaryl etc.. Non sulfonylurea drugs represent only repaglinide and nateglinide resistance. Their common primary function is to stimulate islet cells, which secrete insulin, which lowers blood sugar. However, hypoglycemia can lead to hypoglycemia if dose is inappropriate or does not mix with carbohydrate intake. As they enter the body, they need some time to stimulate the islet cells that produce insulin. Therefore, the best time to take the medicine is 30 minutes before the meal. The main difference between the members is mainly the strength and the length of time. There is no proper combination between members. In order of development: tolbutamide (tolbutamide), chlorpropamide (chlorpropamide) is the first generation of sulfonylurea drugs; glibenclamide (glibenclamide), Glenn Bridget (gliclazide), glipizide, Gliquidone (glipizide) (Gliquidone) is the second generation sulfonylurea drugs represent the third generation sulfonylurea; on behalf of sulfonylurea drugs currently only glimepiride (g