离心泵对小儿体外循环血小板功能的影响（Effect of centrifugal pump on platelet function in children undergoing cardiopulmonary bypass）.docVIP

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离心泵对小儿体外循环血小板功能的影响（Effect of centrifugal pump on platelet function in children undergoing cardiopulmonary bypass）.doc

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离心泵对小儿体外循环血小板功能的影响（Effect of centrifugal pump on platelet function in children undergoing cardiopulmonary bypass）

离心泵对小儿体外循环血小板功能的影响（Effect of centrifugal pump on platelet function in children undergoing cardiopulmonary bypass） Effect of centrifugal pump on platelet function in children undergoing cardiopulmonary bypass Source: Chinese Paper Download Center [07-11-16 14:31:00] editor: studa20 Authors: Zhou Chengbin, Zhang Jingfang, Zhang Xiaohua, Chen Ping, Zhuang Jian, Chen Xinxin [Key words] platelet function Abstract: Objective To investigate the effect of centrifugal pump on platelet function in children undergoing cardiopulmonary bypass (CPB). Methods 20 children with complex congenital heart disease were randomly divided into two groups: centrifugal pump group (n=10) and roller pump group (n=10). The centrifugal pump group uses the centrifugal pump (Biopump BP50 pump head), the roller pump group uses the Stockert III heart lung machine (roller pump), the routine establishment CPB, carries on the cardiac malformation radical cure. Respectively before anesthesia (T1), CPB (T2) at the end, after the end of CPB 24h (T3) blood was measured the platelet count, platelet granule membrane protein -140 (GMP-140), thromboxane B2 (TXB2) and 6- ketone - prostaglandin F1 alpha (6-keto-PGF1 alpha). Results there was no significant difference in CPB time, blocking time and minimum nasopharyngeal temperature between the two groups. The platelet count decreased in group T2 and group two (P 0.05), and there was no significant difference between the two groups. In group T2, the GMP-140 increased in two groups (P 0.05), while in roller pump group, the increase was more significant (P 0.05); the level of TXB2 and 6-keto-PGF1 in roller pump group was higher than that in centrifugal pump group (P 0.05). The volume of pleural fluid in the centrifugal pump group after operation was significantly less than that in the roller pump group (6.4 + 4.1) ml/kg, and in the roller pump group (11.1 + 3.3) ml/kg, P 0.05]. There was no significant difference in blood volume and ICU time between the two gr