human umbilical cord blood-derived cd34+ cells reverse osteoporosis in nodscid mice by altering osteoblastic and osteoclastic activities人类脐带血液cd34 +细胞逆转骨质疏松nodscid老鼠通过改变成骨细胞的和监测活动.pdfVIP

Human Umbilical Cord Blood-Derived CD34+ Cells Reverse Osteoporosis in NOD/SCID Mice by Altering Osteoblastic and Osteoclastic Activities 1 1 1 1 1 2 Reeva Aggarwal , Jingwei Lu , Suman Kanji , Matthew Joseph , Manjusri Das , Garrett J. Noble , 3 4 2 4 3 5 Brooke K. McMichael , Sudha Agarwal , Richard T. Hart , Zongyang Sun , Beth S. Lee , Thomas J. Rosol , 6 7 1 1 Rebecca Jackson , Hai-Quan Mao , Vincent J. Pompili , Hiranmoy Das * 1 Cardiovascular Stem Cell Research Laboratory, Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Columbus, Ohio, United States of America, 2 Department of Biomedical Engineering, College of Engineering, The Ohio State University, Columbus, Ohio, United States of America, 3 Department of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America, 4 Division of Oral Biology, Department of Orthopedics, College of Dentistry, The Ohio State University, Columbus, Ohio, United States of America, 5 Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America, 6 Division of Endocrinology, Diabetes and Metabolism, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America, 7 Department of Materials Science and Engineering, John’s Hopkins University, Baltimore, Maryland, United States of America Abstract Background: Osteoporosis is a bone disorder associated with loss