genetic structure of chimpanzee populations黑猩猩种群的遗传结构.pdfVIP

Genetic Structure of Chimpanzee Populations 1 2 3 1* 2,4* Celine Becquet , Nick Patterson , Anne C. Stone , Molly Przeworski , David Reich 1 Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America, 2 Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, 3 School of Human Evolution and Social Change, Arizona State University, Tempe, Arizona, United States of America, 4 Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America Little is known about the history and population structure of our closest living relatives, the chimpanzees, in part because of an extremely poor fossil record. To address this, we report the largest genetic study of the chimpanzees to date, examining 310 microsatellites in 84 common chimpanzees and bonobos. We infer three common chimpanzee populations, which correspond to the previously defined labels of ‘‘western,’’ ‘‘central,’’ and ‘‘eastern,’’ and find little evidence of gene flow between them. There is tentative evidence for structure within western chimpanzees, but we do not detect distinct additional populations. The data also provide historical insights, demonstrating that the western chimpanzee population diverged first, and that the eastern and central populations are more closely related in time. Citation: Becquet C, Patterson N, Stone A, Przeworski M, Reich D (2007) Genetic structure of chimpanzee populations. PLoS Genet 3(4): e66. doi:10.1371/journal.pgen. 0030066 Introduction showing discontinuity among chimpanzee populations [6–10], potentially at odds with the model proposed by Fischer et al.