from disease association to risk assessment an optimistic view from genome-wide association studies on type 1 diabetes从疾病相关风险评估一个乐观的观点从全基因组关联研究1型糖尿病.pdfVIP
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from disease association to risk assessment an optimistic view from genome-wide association studies on type 1 diabetes从疾病相关风险评估一个乐观的观点从全基因组关联研究1型糖尿病
From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes 1. 2. 3 2 2 2 Zhi Wei , Kai Wang , Hui-Qi Qu , Haitao Zhang , Jonathan Bradfield , Cecilia Kim , Edward 2 2 2 2 4 5 Frackleton , Cuiping Hou , Joseph T. Glessner , Rosetta Chiavacci , Charles Stanley , Dimitri Monos , 2,6 3 2,6 Struan F. A. Grant , Constantin Polychronakos , Hakon Hakonarson * 1 Department of Computer Science, New Jersey Institute of Technology, Newark, New Jersey, United States of America, 2 Center for Applied Genomics, The Children’s ´ Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, 3 Departments of Pediatrics and Human Genetics, McGill University, Montreal, Quebec, Canada, 4 Division of Endocrinology, Department of Pediatrics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, 5 Department of Pathology and Laboratory Medicine, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, 6 Division of Genetics, Department of Pediatrics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America Abstract Genome-wide association studies (GWAS) have been fruitful in identifying disease susceptibility loci for common and complex diseases. A rema
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