党参对鼠j 774巨噬细胞吞噬活性的增强效应(Enhancing effect of Codonopsis pilosula on phagocytosis of murine J 774 macrophages).docVIP
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党参对鼠j 774巨噬细胞吞噬活性的增强效应(Enhancing effect of Codonopsis pilosula on phagocytosis of murine J 774 macrophages)
党参对鼠j 774巨噬细胞吞噬活性的增强效应(Enhancing effect of Codonopsis pilosula on phagocytosis of murine J 774 macrophages) Enhancing effect of Codonopsis pilosula on phagocytosis of murine J 774 macrophages Update Date: 2011-01-24 Click: Jia Taiyuan, Benjamin, H.S., Lau Abstract: Objective: To study the enhancing effect of Codonopsis pilosula on immune function and explore its mechanism. Methods: the water extract of Codonopsis pilosula was added into mouse J 774 macrophage culture medium for micro cell culture, and the activity of phagocytosis was directly detected by automatic micro fluorescence analyzer. Result: the results showed that the water extract of Codonopsis liquid on the phagocytic activity of macrophages has been enhanced, at the concentration of 500 ~ 3000 g/ml, and the drug control group (O) comparison has significant difference (P 0.05), enhanced 1.33 ~ 1.70 times respectively. Conclusion: macrophage is one of the important immune cells, each part of the bodys immune response plays a key role, can enhance the immune effect of Dangshen, may be achieved through the enhancement of macrophage immune activity. Keywords: Codonopsis pilosula; J 774 macrophage strain; oxygen explosion CLC number: R285.5, document identification code: A, article number: 1008-0805 (2000) 09-0769-02 The, Enhancing, Effect, of, Chinese, Medicine, Radix, Pilosulae, on, J,, Macrophage JIA Tai-yuan (Xian, Central, Hospital, Xian, 710003, China) Benjamin H.S. Lau (Department, of, Microbiology, School, of, Medicine, Loma, Linda, University, Loma, Linda, CA, 92354, USA) Abstract:Objective: To probe into the mechanism of the enhancing effect of Chinese medicine Radix Codonopsis (CR) on organic immune activity. Method: The murine macrophage J line was chosen to 774 cell cultured with CR aqueous extract in different concentrations and then, the phagocytic activity was measured directly using a computerized microplate fluorometer. Result: The phagocytosis of macrophage J 774 was enhanced significantly
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