11～13+6孕周正常胎儿静脉导管血流频谱参数分析.DOCVIP

11～13+6孕周正常胎儿静脉导管血流频谱参数分析 赵雪婷，漆洪波 （400016 重庆，重庆医科大学附属第一医院妇产科） [摘要] 目的 测量分析在11～13+6孕周正常胎儿静脉导管（DV）各血流频谱参数与孕周的关系，建立各自参考曲线。方法　选取11～13+6孕周在我科行超声检查的单胎孕妇904名，进行胎儿DV多普勒血流检查，分别测量心室收缩期血流峰值（S-wave）、心室舒张早期血流峰值（D-wave）、心房收缩期血流速度（A-wave）、平均时间最大血流速度（TAMXV）、搏动指数（PI）、前负荷指数（PLI）、心室收缩期血流峰值/心房收缩期血流速度（S/A）。随访妊娠结局，503名正常妊娠孕妇纳入研究。结果：S–wave(r=0.237，P＜0.01)、D–wave(r=0.251，P＜0.01)、A–wave(r=0.217，P＜0.01)、TAMXV(r=0.272，P＜0.01)与孕龄显著正相关，PIV（r=-0.159，P =0.006）与孕龄显著负相关；PLI（r=-0.096，P =0.098）、S/A（r=-0.089，P =0.128）与孕龄无相关性。结论　孕早期胎儿DV血流速度随孕周增加而增加，PI随孕周增加而降低，PLI和S/A无显著变化。 [关键词]　静脉导管；多普勒；超声；搏动指数 [中图法分类号] [文献标志码] A Correlation of ductus venosus Doppler velocimetric parameters with gestation period in ?fetus venosus between 11 and 13+6 weeks of gestation Zhao Xueting, Qi Hongbo (Department of Obstetrics and Gynecology, First Affiliated Hospital, Chongqing Medical University, Chongqing, 400016, China) [Abstract] Objective: To investigate the correlation of ductus venosus Doppler velocimetric (DV) parameters with gestation period in women at 11 to 13+6 weeks gestation in normal pregnancies. Methods: A prospective observational study was performed on 904 pregnant women who underwent ultrasound examination during 11 to 13+6 weeks of gestation in our department from July 2011 to January 2013. The following variables of the ductus venosus were measured: peak velocity during ventricular systole (S-wave), peak velocity during ventricular diastole (D-wave), lowest forward velocity during atrial contraction (A-wave), time-average maximum velocity (TAMXV), pulsatility index for vein (PIV), preload index (PLI), and the ratio of maximum peak systolic velocity during ventricular systole to end-diastolic velocity during atrial contraction (S/A). Pregnant outcomes were followed up. Finally a total of 503 normal pregnancies out of 904 pregnant women were analyzed. Results: There were significant increase for the S-wave (r=0.237, P＜0.01), Dwave (r=0.251, P＜0.01), Awave (r=0.217, P＜0.01), TAMXV (r=0.272,