急性白血病患者首程化疗前后血小板计数的临床意义（Clinical significance of platelet count before and after primary chemotherapy in patients with acute leukemia）.docVIP

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2017-07-24 发布于河南
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急性白血病患者首程化疗前后血小板计数的临床意义（Clinical significance of platelet count before and after primary chemotherapy in patients with acute leukemia）.doc

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急性白血病患者首程化疗前后血小板计数的临床意义（Clinical significance of platelet count before and after primary chemotherapy in patients with acute leukemia）

急性白血病患者首程化疗前后血小板计数的临床意义（Clinical significance of platelet count before and after primary chemotherapy in patients with acute leukemia） Clinical significance of platelet count before and after primary chemotherapy in patients with acute leukemia 2010-07-02 Wu Yi Hong Zhu Wenjuan Acute leukemia patients are often associated with bleeding tendency, especially during the induction chemotherapy. It is one of the important causes of chemotherapy failure and early death. The concurrent bleeding is closely related to the decrease of platelet count (BPC) in patients. BPC15 x 109/L has been regarded as one of the indicators of poor prognosis in acute leukemia. After induction chemotherapy of BPC decreased further, but many have picked up in complete remission before the dynamic observation of BPC decline or recovery time than the initial BPC more prognostic value, this paper reviews the analysis there is a certain relationship between 64 cases of acute leukemia patients before and after the first course of chemotherapy BPC and subsequent remission rate. 1 clinical information 1.1 general data, 64 cases of acute leukemia are all newly treated adult patients. The clinical, hemogram and marrow images are diagnosed and classified according to the document [1] standard. Male 43 cases, female 21 cases, aged 16 to 72 years old, the average age of 35.9; including 19 cases of acute lymphocytic leukemia, 45 cases of acute non lymphocytic leukemia (M1 7 cases, M2 18 cases, M3 6 cases, M4 5 cases, M5 6 cases, M6 3 cases). 1.2 courses of chemotherapy for acute lymphoblastic leukemia were selected by DVP and DVLP regimens (D: daunorubicin, V: vincristine, L: L-asparaginase, P: prednisone), conventional dose, treatment for 4 weeks. In acute non lymphocytic leukemia, M3 was administered with all trans retinoic acid 60mg/d for 40~45 days. The other subtypes of random selection of DA3 ~ 7, HA5 ~ 7, MA5 ~ 5 (D: A: daunorubicin, Ara-C, H: homoharringtonine, M: mitoxantrone), conventional dose. 1