克林霉素说明书（Clindamycin manual）.docVIP

克林霉素说明书（Clindamycin manual） clindamycin hydrochloride injection Indication: Department of Obstetrics and Gynecology, Department of general surgery, neurology, cardiothoracic surgery, respiratory medicine, aspiration pneumonia, empyema, pulmonary abscess, osteomyelitis, peritonitis, pelvic inflammation usage and dosage Intramuscular injection or intravenous drip. Adults: 0.6 to 1.2g a day, divided into 2~4 applications; serious infection: 1.2 to 2.4G a day, divided into 2~4 intravenous drip. Children over 4 weeks and 4 weeks: 15 to 25mg/kg per day, divided into 3~4 applications; severe infection: 25 to 40mg/kg per day, and divided into 3~4 applications. The dosage of intramuscular injection of this product should not exceed 1 600mg, more than this dosage should be changed to intravenous administration. The speed of intravenous administration should not be too fast. 600mg should be added to the infusion of no less than 100ml, with at least 20 minutes infusion. 1 hours, enter the dose of not more than 1200mg. Adverse reaction 1, gastrointestinal reactions: common nausea and vomiting, abdominal pain, diarrhea; severe cases of abdominal angina, abdominal pain, severe diarrhea (water or pus like), fever, abnormal thirst and fatigue (pseudomembranous colitis). Diarrhea, colitis and pseudomembranous colitis can occur in the initial stage of medication, also can produce several weeks after drug withdrawal. 2. The blood system: sometimes can reduce the white blood cell, the neutrophilic granulocyte, the eosinophilia and the thrombocytopenia, and so on. Rare aplastic anemia. 3, allergic reactions: visible rash, itching, etc., occasionally urticaria, vascular edema and serum sickness reaction; rarely exfoliative dermatitis, bullous dermatitis, erythema multiforme and Steven-Johnson syndrome. 4, liver and kidney function abnormalities, such as elevated serum aminotransferase, jaundice and so on. 5. Intravenous drip may cause phlebitis. Intramuscular injection may cause pain, ind