螺旋藻藻蓝蛋白光敏作用的研究进展 - 生命科学.pdf

20 2 Vol. 20, No. 2 2008 4 Chinese Bulletin of Life Sciences Apr., 2008 1004-0374(2008)02-0283-04 (1 300134 2 010018) Q949.225; Q946.1A Progress of the studies on photosensitization from Spirulina phycocyanin 1 1 2 1 FAN Min , WANG Xue-qing *, DUAN Kai-hong , PANG Guang-chang (1 Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology and Food Science, Tianjin University of Commerce , Tianjin 300134, China; 2 College of Bioengineering, Inner Mongolia Agricultural University, Huhhot 010018, China) Abstract: Phycocyanin extracted from Spirulina possesses many kinds of biological functions including the effects of antitumor and enhancing the immunity, etc. The phycocyanin may be used as a prosperous photo- sensitizer and possibly applied to the photodynamic therapy of cancers. The structure, photosensitization of phycocyanin and the principles of photodynamic therapy were mainly reviewed. And the application status and prospects of the photodynamic therapy of the phycocyanin are introduced. Key words: Spirulina ; phycocyanin; photodynamic therapy; photosensitizer (Spirulina) [4] PDT PC 35 1 (phycocyanin, PC) PC 30k αβ 100% 15k PC (αβ) [4,5] 3 (αβ)6 PC (apoprotein) [1,2] (photodynamic therapyPDT) 2007-12-24 2008-02-28 (06YFGZNC04200);