肝血虚证15 项实验指标同步检测的分析 - 中南大学学报（医学版）.pdf

2001,26(4) BULL HUNAN ED UNIV 337 15 1 1 2 1 1 1 1 陈昌华 , 石林阶, 舒毅刚 , 陈国林 , 邢之华 , 张自强 , 尤劲松 ( 1 中南大学湘雅医院中西医结合研究所; 2 血液科, 长沙410008) [ ] 采用高效液相色谱(HPLC- ED)法和放射免 法( RIA), 对27例肝血虚证患者 15 项指标进行检测, 经多 因素聚类分析, 并进行典型指标筛选结果发现:15 项指标可聚五类, 每类的典型指标分别为NE, T ,TXB , ALD 和 3 2 cG P提示肝血虚证的病理基础主要以交感神经活动减退, 低T 综合征,调节心血管舒缩和水盐代谢的活性物质以 3 及细胞膜内第二信使类物质的显著改变为特征 [ ] 肝血虚证; 贫血, 低色素性; 贫血, 再生障碍性; 病理生理学; 多元分析; 聚类分析 [ ] R2- 03 [] A [ ] 2001 Simultaneously Analysis of 15 Parameters in the Patients With the Liver- Blood Deficiency Syndrome CHEN Changhua, SHILinjie, SHU Yigang, et al ( Institute of Combined Traditional Chinese and Western Medicines, Xiangy a H osp ital, Central South University, Changsha 410008, China Abstract: Objective UsingHPLC- ED or RIA, we determned simultaneously 15 indexes in 27 patients withthe liver- blood deficiency syndrome (LDBD). By means of multivarivate hierarchical cluster analysis and selections oftypicalvariate, the results showedthat 15 indexeswere classified into5 groups, andthetypical vari ates of each groups were NE, T , TXB , ALD and cG P. It suggests that LBDS has some pathopysiologyical 3 2 characteristics such as decreased functions of sympatehetic nerve activation, lowerT syndrome, imbalanceof the 3 active substance regulating cardiovascular function and metabolism of salt and water, and abnormalities second signal substance in cellular membra