老年糖尿病患者的治疗策略.pptVIP

China in 2010 11.6% prevalence of diabetes in adults in China in 2010 based on cross-sectional study of 98,658 adults in China in 2010 estimated prevalence any diabetes in 11.6% (12.1% in men and 11% in women) prediabetes in 50.1% Reference - JAMA 2013 Sep 4;310(9):948, editorial can be found in JAMA 2013 Sep 4;310(9):916 Background Diabetes mellitus type 2 is a common endocrine disorder characterized by variable degrees of insulin resistance and deficiency, resulting in hyperglycemia. It is often identified through routine screening beginning in middle age, or through targeted screening of adults with risk factors such as obesity, metabolic syndrome, polycystic ovary syndrome, a history of gestational （妊娠期的）diabetes, or other concerning familial, clinical, or demographic characteristics. Also called diabetes mellitus type II type 2 diabetes type II diabetes non-insulin-dependent diabetes mellitus (NIDDM) adult-onset diabetes（成人型） insulin-resistant diabetes Who is most affected persons with obesity(2) mean age at diagnosis of type 2 diabetes in United Stated decreased from 52 years in 1988-1994 to 46 years in 1999-2000 (Ann Fam Med 2005 Jan-Feb;3(1):60?full-text) diabetes prevalence similar in men and women globally, but slightly higher in men 60 years old and in women at older ages (Diabetes Care 2004 May;27(5):1047?full-text) American Indians/Alaska Natives (AI/ANs) have higher prevalence of diabetes from 1994 to 2002, age-adjusted prevalence of diabetes among United States adults increased from 4.8% to 7.3%, but among AI/AN adults, from 11.5% to 15.3% (MMWR Morb Mortal Wkly Rep 2003 Aug 1;52(30):702?full-text) from 1994 to 2004, age-adjusted prevalence of diagnosed diabetes in AI/ANs 35 years old increased from 0.85% to 1.71%; prevalence in 2004 increased with age from 0.22% at age 15 years to 4.68% at ages 25-34 years (MMWR Morb Mortal Wkly Rep 2006 Nov 10;55(44):1201?full-text) Likely risk factors Prediabetes impaired fasting glucose（空腹血糖受损） - plas