呼吸系统疾病--课件.pptVIP

* * * * * Figure 7. Pathologic cytoarchitectural changes indicative of diffuse alveolar damage, as well as a multinucleated giant cell with no conspicuous viral inclusions. * * * * With Gomori methenamine silver stain, Pneumocystis carinii in lung is demonstrated by the appearance of brown to black cysts in the alveolar exudate. * * 谢 谢 大 家！ * * * * * * * * * * * Lobar pneumonia- gray hepatization, gross photograph. The lower lobe is uniformly consolidated. * * * 感染性休克septic shock 胸腔积液pleural effussio N 心肌炎infective cardiomyopathy * 肉眼检查：左肺上、下叶均发生实变。 肉眼检查：左肺上、下叶均发生实变。 * * * * * congestion充血、拥挤的 Consolidation实变 The cut surface of this lung demonstrates the typical appearance of a bronchopneumonia with areas of tan-yellow consolidation. Remaining lung is dark red because of marked pulmonary congestion. Bronchopneumonia (lobular pneumonia) is characterized by patchy areas of pulmonary consolidation. These areas become almost confluent in the left lower lobe on the bottom left of the photograph.The areas of consolidation are firmer than the surrounding lung. The cut surface of this lung demonstrates the typical appearance of a bronchopneumonia with areas of tan-yellow consolidation. Remaining lung is dark red because of marked pulmonary congestion. Bronchopneumonia (lobular pneumonia) is characterized by patchy areas of pulmonary consolidation. These areas become almost confluent in the left lower lobe on the bottom left of the photograph.The areas of consolidation are firmer than the surrounding lung. The consolidated areas here very closely match the pattern of lung lobules (hence the term lobular pneumonia). * * * * * * * * 流感病毒呈球形，直径80-120nm，由脂质外膜包绕RNA核蛋白核心组成，M1蛋白排列于膜上，病毒表面有两种结构：杆状的血凝素和蕈状的神经氨酸酶，这些都是病毒复制所需要的蛋白 流感是高度传染性疾病，能通过咳嗽或喷嚏形成的含病毒的水滴进行传播，吸入后，病毒颗粒沉积在整个上下呼吸道，迅速进行复制，在1-3天的潜伏期内，携毒者会不知觉地向其他人进行传播。感染1-2天后突然出现症状，包括发热、寒战、头痛、肌痛、不适或咳嗽，这些症状与病毒复制高峰有关。症状出现后感染者还可以向其他人病毒4-6天。 流感病毒的生活周期。　　(a) 病毒通过血凝素结合宿主细胞表面,进入细胞 (b)进行复制 (c)在宿主细胞内，新合成的病毒在细胞表面出芽 (d)在神经氨酸酶作用下从细胞释放 (e