新型低弹性模量医用β钛合金Ti2448椎弓根螺钉内固定影响胸椎稳定性的生物力学测试.docVIP

新型低弹性模量医用β钛合金Ti2448椎弓根螺钉内固定影响 胸椎稳定性的生物力学测试 黄象望，刘宏哲(湖南省人民医院骨科，湖南省长沙市 410000) 引用本文：黄象望，刘宏哲. β钛合金Ti2448椎弓根螺钉内固定影响胸椎稳定性的生物力学测试[J].中国组织工程研究，2017，21():1031-1035. DOI:10.3969/j.issn.2095-4344.2017.07.009 ORCID: 0000-0003-3448-9230(黄象望 文题释义： 新型医用β钛合金脊柱内固定系统β钛合金Ti2448(Ti-24Nb-4Zr-7.9Sn)是迄今为止初始杨氏模量最低的钛合金，其初始杨氏模量约40 GPa，平均杨氏模量 20 GPa，抗拉强度约900 MPa，与人体组织的生物相容性和力学相容性优异。 目的：探讨新型低弹性模量脊柱椎弓根螺钉内固定系统的生物力学性能，并与Ti6Al4V椎弓根螺钉进行比较。 方法：取60个新鲜人尸体胸椎椎体标本，随机选择一侧椎弓根置入新型低弹性模量Ti2448椎弓根螺钉，另一侧椎弓根置入Ti6Al4V椎弓根螺钉，检测两组螺钉的最大弯曲载荷与最大载荷时位移、最大旋入力矩及最大轴向拔出力。 结果与结论：两组螺钉的最大弯曲载荷、最大载荷时位移、最大旋入力矩、最大拔出力比较差异均无显著性意义。结果表明，新型低弹性模量Ti2448椎弓根螺钉内固定系统的最大弯曲强度、最大旋入力矩、最大拔出力与Ti6Al4V螺钉基本一致，可满足脊柱生物力学在内固定强度方面的需求。 关键词： 骨科植入物；脊柱植入物；脊柱；椎弓根螺钉；内固定系统；弹性模量；生物力学；载荷；弯曲；位移；性能 主题词： 假体，植入物；脊柱；生物力学；组织工程 专利： 实用新型专利研究相关文章：专利号：ZL2015 2 0164377.0 一种胸腰椎椎弓根手术用套件 A new low elastic modulus of beta titanium alloy Ti2448 spinal pedicle screw fixation affects thoracic stability: biomechanical analysis Huang Xiang-wang, Liu Hong-zhe (Department of Orthopedics, Hunan Provincial People’s Hospital, Changsha 410000, Hunan Province, China) Abstract BACKGROUND: A new type of medical titanium alloy Ti2448 (Ti-24Nb-4Zr-7.9Sn) is by far the lowest initial modulus of titanium alloy, with the initial modulus of about 40 GPa, the average Young’s modulus 20 GPa, and tensile strength of about 900 MPa; human tissue biocompatibility and mechanical compatibility are excellent. OBJECTIVE: To investigate the biomechanical properties of a new low elastic modulus spinal pedicle screw fixation system and compare it with Ti6Al4V pedicle screw. METHODS: Totally 60 fresh human cadaveric thoracic vertebrae were randomly selected: on one side, pedicle new low modulus Ti2448 pedicle screws, as the experimental group; on the other side, pedicle screw Ti6Al4V, as control group. The maximum bending load and maximum load displacement, maximum torque and maximum axial pulling force of the two groups were detected. RESULTS AND CONCLUSION: There was no significant difference i