人乳多不饱和脂肪酸含量与婴儿食物过敏关系的研究.pdfVIP

中国儿童保健杂志 2011 年 01 月第 19 卷第 1 期 CJCH C JAN. 2011, Vol 19, No. 1 65 文章编号: 1008-6579( 2011) 01- 0065-03 =临床研究与分析 人乳多不饱和脂肪酸含量与婴儿食物过敏关系的研究 黄于娟, 黎海芪 ( 重庆医科大学附属儿童医院儿童保健 科, 重庆 400014) 中图分类号: R174 文献标识码: A 摘 要: = 目的 研究人乳多不饱和脂肪酸( polyunsaturated fatty acid, P U FA ) 含量与婴 儿发生 食物过 敏的关 系。 =方法 采集 3~ 6 月人 乳喂养婴儿母亲的乳汁, 高效液相色谱法法检测其中 A- L N A、DH A( n- 3 组) 和 L A 、A A 含 量( n- 6 组) ; 按 R. Sporik 标准确立婴儿食物过敏, 比较食物过敏与正常婴儿母亲乳汁中 PU F A 含量的差异性。 =结果 31 例 3~ 6 月龄人乳喂养婴儿中 10 例发生食物过敏, 过敏 婴儿母 亲乳汁 中 L A 、AA 及 A- L N A 含 量增高( P 0. 05) 、DHA 含量 差异无统计学意义。 = 结论 食物过敏婴儿的母亲乳汁中 A- L NA 、LA 、AA 含量升高, 提示人乳 PU F A 代谢异常可能与 婴儿发生食物过敏有关。 关键词: 人乳; 多不饱和脂肪酸; 食物过敏; 婴儿 Correlation between contents of polyunsaturated fatty acid in human breast milk and food allergy in infants. H UA N G Y u- j uan , L I H ai-qi . ( Department of Child Health Care, Childrens Hospital of Chongqing Medical University , Chongqing 400014, China) Abstract: = Objective T o explo re the co rrelatio n between co ntents o f A- L NA 、DHA 、A A and L A in human milk and the dev elopment of foo d allergy in infants. = Methods Cross- sectional study was conducted; breastfed infant s ag ed 3~ 6 months w ere enro lled as w ell as their mothers; human milk samples were collected in the out- patient clinic, content s of PU- FA s in human milk w ere analysed w ith H PL C method. Infant s were diag no sed as food allerg y according to R. Sporiks meth- od in our out- patient clinic. = Results 10 infants were diag no sed as food allergy , and 21 norma l as contro l. Content s of A- L N A、A A and L A in human milk of foo d- allergy g roup w ere higher than tho se in contro l g ro up( P 0. 05) , ex cept the co