2 body fluid体液(王勇).ppt

Body fluid Body fluid is body water and its dissolved solutes . Total body water makes up approximately 55 to 60% of body weight in adult males and somewhat less, perhaps 50 to 55%, in adult females (due to a higher proportion of body fat). 体液 Compartments of body fluid Fluid found within the cells is called intracellular fluid (ICF) and that found outside cells is called extracellular fluid (ECF). Approximately 2/3 of body fluid is intracellular and 1/3 is extracellular. Of the ECF approximately 80% is interstitial fluid and 20% is blood plasma. Lymph Cerebrospinal fluid Synovial(滑液) Aqueous humour/vitreous body of the eyes Endolymph/perilymph in the ears Pleural, pericardial and peritoneal fluid between serous membranes Glomerular filtrate in the kidneys. Constitutes of body fluid * * yongwang@stu.edu.cn 体液分布 Compartment Volume (in Liters) Percentage of body fluid Percentage of body weight Total body fluid (TBF) 42 100 60 Intracellular fluid (ICF) 28 67 40 Extracellular fluid (ECF) 14 33 20 Plasma 2.8 6.6 (25% of ECF) 5 Interstitial fluid 11.21 26.4 (75% of ECF) 15 Lymph Negligible Negligible Negligible Transcellular fluid Negligible Negligible Negligible Newborn 75 45 4 26 30 Men 60 40 5 15 20 Women 50 35 4 11 15 Plasma Interstial fluid Total Age TBW ICF ECF Whose body contains more water? Why? Different cell types have different water content: Muscle?cells 50% Bone?cells 22% Fat?cells 10% ECF Blood plasma Interstitial fluid Represents about 90% of extracellular cations. Level in blood controlled by aldosterone, ANP, and ADH. Essential role in fluid and electrolyte balance – accounts for half the osmolarity of ECF. Role in generation of action potentials. Distribution Function Sodium (Na+) Most abundant intracellular cation. Blood serum level controlled by aldoster