专效抗敏牙膏用于缓解牙本质敏感症的疗效观察.docVIP

专效抗敏牙膏用于缓解牙本质敏感症的疗效观察 北京小汤山医院 口腔科 刘侠 牛国卫 刘春秀 肖英 张磊 [摘要] 目的: 评价专效抗敏感牙膏缓解牙本质敏感的效果。方法: 选取2011年1~ 9月就诊于我院口腔科牙本质敏感症60例, 患牙106颗。其中男性37例、女性23例, 年龄28~ 65岁。牙本质敏感的评价采用冷空气喷吹法,受试者确认是否敏感, 采用数字化疼痛评判法 visual analogue scale, VAS 记录受试者的敏感程度。按照临床试验研究受试者纳入和排除标准纳入受试者。采用高露洁专效抗敏感牙膏每天刷牙两次, 每次3分钟, 4周后回访受试者。结果: 4周后完全改善的患牙27颗, 部分改善的患牙56颗, 无改善的患牙23颗, 改善牙本质敏感症的有效率达78.30% ，治疗后同治疗前相比较,所有患牙以及磨牙、前磨牙、前牙的VAS值均有显著下降, P值﹤0.01 差异有统计学意义。结论: 临床试验结果表明高露洁专效抗敏感牙膏可有效缓解牙本质敏感。 [关键词] 牙本质敏感; 抗敏感牙膏; 数字化疼痛评判法 A clinical study on the effectiveness of desensitizing toothpaste in patients with dentinehypersensitivity LIU Xia, NIU Guo-wei, LIU Chun-xiu. XIAO Ying, ZHANG Lei Xiaotangshan Hospital, Beijing 102211, China [Abstract]Objective：To evaluate the clinical effects of Colgate desensitizing toothpaste on dentine hypersensitivity. Methods:60 subjects 106 teeth were recruited into the study,37 were male 23 were female ,age 28-65 years old.The dentine hypersensitivity was evaluated by a subject self perceived short sharp pain in visual analogue scale VAS in response to a blast of cold air from a triple syringe adm in istered to a tooth surface in 1 cm. The subjects were asked to brush their teeth with Colgate desensitizing toothpaste twice a day, and at three minutes each time for 4 weeks. Results:There were significant reductions of 78.30% in air blast stimulated hypersensitivity after 4 weeks .The mean post- application VAS values were statistically significant decreased compared to the base line measurements P 0. 01 . Conclusion：Results of the clinical trial showed that Colgate desensitizing toothpastes were effective in reducing dentine hypersensitivity KEY WORDS：Dentin hypersensitivity; Desensitizing toothpaste; Visua lanalogue scale 牙本质敏感症指牙齿遇到冷热酸甜等食物时所出现的短瞬疼痛或不适。暴露的牙本质在机械、化学、温度或渗透压的刺激下，所表现的一种尖锐、短暂的疼痛或不适症状，发作时间短暂，随刺激结束而消失，并且这种疼痛不伴有牙齿其他方面的缺陷或病理状况。牙本质敏感在我国人群中很常见, 流行病学调查显示〔1-3〕我国有29. 7% 的成人罹患牙本质敏感。临床实践证明，有两种方法可以降低或消除牙本质敏感，即通过药物制剂的作用降低局部神经敏感性和 或 形成沉淀物阻塞暴露的牙本质小管，隔绝刺激的传导。降低神经敏感性的药物有：柠檬酸钾、硝酸钾等各种钾盐。这些