参考资料--乳品中抗生素残留检测方法研究进展.docxVIP

南京林业大学乳品中抗生素残留检测方法研究进展Review on the Methods for Determination of Antibiotic Residues in Milk Products侯雯食品科学与工程森林资源与环境学院指导老师：石瑞2011/12/22[在此处键入文档的摘要。摘要通常是对文档内容的简短总结。在此处键入文档的摘要。摘要通常是对文档内容的简短总结。]乳品中抗生素残留检测方法研究进展侯雯 南京林业大学 森林资源与环境学院 江苏南京 210037摘 要随着我国奶牛饲养业的日益发展，多种抗生素被越来越多地被应用于饲料添加剂和预防奶牛疾病中,不可避免地产生了乳品抗生素的残留。乳品中残留的抗生素不但危害人体的健康,造成人体免疫力的降低， 同时也会影响牛奶的品质，经济蒙受损失，对正常贸易产生负面影响。文章从牛乳中抗生素残留的现状、来源、产生的危害、目前所用的检测方法以及近期检测方法的研究进展等方面进行综述，并对控制抗生素残留提出了相关的建议。本文为加强我国对乳制品中抗生素的检测监督，解决目前乳品工业发展中面临的一些问题提供了参考。关键词：乳品; 抗生素残留;微生物法;高效液相色谱法;免疫法Review on the Methods for Determination of Antibiotic Residues in Milk ProductsHouwenForest Resources and Environment, Nanjing Forest University, Nanjing Jiangsu Province,210037Abstract：With an increasing development of the milk industry in our country, multi- antibiotics have been applied widely to the feed additives and the preventing and treating diseases of dairy cattle ,which inevitably produces residues in milk. The antibiotic residues in milk not only do damage to people’s health, causing hypoimmunity ,but also have negative effects on the quality of the milk , incuring economic losses .What is worse, it will hamper the normal import and export trade at the same time .The paper provides an overview on the present situation ,provenances, and the harm of milk antibiotic residues .It also introduces current methods applied to determine milk antibiotic residues and the development of the test methods. Some suggestions are put forward to control the antibiotic residues. Moreover, the paper provides a reference for enhancing the detection and monitoring in milk production and solving the problems of milk industry faced with right now.Key words : Milk ;Antibiotic Residues; Microbiological Methods; HPLC; Immunoassays 目 录引言11乳品中抗生素的现状12乳品中抗生素残留的来源,种类及其危害12.1乳品中抗生素的来源12.1.1防治乳牛疾病使用的内服或外用抗生素在牛体内的残留12.1.2不按规定执行应有的休药期12.1.3不按卫生规范和程序操作引起抗生素残留22.1.4使用违禁或淘汰抗生素造成的残留超标22.2乳品中抗生素残留的种类22.2.1β-内酰胺类（β- lactams）22.2.2四环素类（Tetracyclines,TCs）22.2.3氨基糖苷类（Aminoglycosides）22.2.4氯霉素类类（