Morbidity After Total Thyroidectomy for Benign Thyroid Disease Comparison of Graves Disease and Non-Graves Disease》.pdfVIP

MORBIDITY AFTER TOTAL THYROIDECTOMY FOR BENIGN THYROID DISEASE: COMPARISON OF GRAVES’ DISEASE AND NON-GRAVES’ DISEASE Feng-Yu Chiang,1,2 Jen-Chih Lin,2 Che-Wei Wu,2 Ka-Wo Lee,1,2 Shang-Pin Lu,3 Wen-Rei Kuo,1,2 and Ling-Feng Wang2 1Department of Otolaryngology–Head and Neck Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, 2Department of Otolaryngology–Head and Neck Surgery, Kaohsiung Medical University Hospital, Kaohsiung, and 3Penghu Hospital, Department of Health, Executive Yuan, Penghu, Taiwan. The purpose of this study was to review the safety of total thyroidectomies for benign thyroid dis- ease, with special emphasis on the comparison between Graves’ disease and non-Graves’ disease. In this study, 107 patients who underwent total thyroidectomies for clinically benign thyroid disease performed by the same surgeon between January 1987 and December 2004 were enrolled; 48 had Graves’ disease and 59 had non-Graves’ disease. The rates of temporary vs. permanent hypopara- thyroidism, hematoma requiring surgical intervention, and temporary vs. permanent recurrent laryngeal nerve palsy (RLNP) after total thyroidectomy for benign thyroid disease were 34.6% vs. 3.7%, 6.5%, and 6.5% vs. 1.85%, respectively. The rates of permanent hypoparathyroidism and tempo- rary RLNP in the Graves’ disease group were significantly different when compared with the non- Graves’ disease group (8.3% vs. 0% and 11.5% vs. 2.5%, respectively). However, comparing the rates of temporary hypoparathyroidism, permanent RLNP, and postoperative hematoma, there was no statistically significant difference. Compared with total lobectomy, the rates of postoperative hema- toma incre