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Executive function as predictors of persistent thought disorder in first-episode schizophrenia A one-year follow-up study》.pdf
Schizophrenia Research 159 (2014) 465–470 Contents lists available at ScienceDirect Schizophrenia Research journal homepage: /locate/schres Executive function as predictors of persistent thought disorder in first-episode schizophrenia: A one-year follow-up study Jia-Qi Xu a,⁎, Christy Lai-Ming Hui a, Julia Longenecker a, Edwin Ho-Ming Lee a, Wing-Chung Chang a, Sherry Kit-Wa Chan a, Eric Yu-Hai Chen a,b a Department of Psychiatry, The University of Hong Kong, Hong Kong b State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong a r t i c l e i n f o a b s t r a c t Article history: Language disorganization is an important clinical indicator of acute psychosis, yet the longitudinal course and Received 30 May 2014 pathogenesis are not well understood. Executive dysfunction has been suggested as a vital contributor to formal Received in revised form 6 August 2014 thought disorder (FTD) and may serve as a stable predictor of symptomatic risk. The paper reports a one-year Accepted 30 August 2014 prospective study of language disorganization in sixty patients with first-episode schizophrenia-spectrum Available online 24 September 2014 disorders and investigates executive function as a predictor of persistent FTD one year after illness onset. FTD was captured using the Clinical Language Disorder Rating Scale (CLANG), which segregates language abnormalities Keywor
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