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Mach Learn (2006) 65:31–78
DOI 10.1007/s10994-006-6889-7
The max-min hill-climbing Bayesian network
structure learning algorithm
Ioannis Tsamardinos · Laura E. Brown · Constantin F. Aliferis
Received: January 07, 2005 / Revised: December 21, 2005 / Accepted: December 22, 2005 / Published
online: 28 March 2006
Springer Science + Business Media, LLC 2006
Abstract We present a new algorithm for Bayesian network structure learning, called
Max-Min Hill-Climbing (MMHC). The algorithm combines ideas from local learning,
constraint-based, and search-and-score techniques in a principled and effective way. It first
reconstructs the skeleton of a Bayesian network and then performs a Bayesian-scoring greedy
hill-climbing search to orient the edges. In our extensive empirical evaluation MMHC out-
performs on average and in terms of various metrics several prototypical and state-of-the-art
algorithms, namely the PC, Sparse Candidate, Three Phase Dependency Analysis, Optimal
Reinsertion, Greedy Equivalence Search, and Greedy Search. These are the first empirical re-
sults simultaneously comparing most of the major Bayesian network algorithms against each
other. MMHC offers certain theoretical advantages, specifically over the Sparse Candidate
algorithm, corroborated by our experiments. MMHC and detailed results of our study are
publicly available at /supplements/mmhc paper/mmhc index.html.
Keywords Bayesian networks · Graphical models · Structure learning
1. Introduction
A Bayesian network is a mathematical construct that compactly represents a joint probability
distribution P among a set variables V . Bayesian networks are frequently employed for
modeling domain knowledge in Decision Support Systems, particularly in medicine (Beinlich
et al., 1989; Cowell et al., 1999; Andreassen et al., 1989).
Editor: Andrew W. Moore
I. Tsamardinos · L. E. Brown ()· C. F. Aliferis
Discovery Systems Laboratory, D
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