_MRA与ASL联合评估TIA患者颅内动脉及灌注.docVIP

MRA与ASL联合评估TIA患者颅内动脉及灌注 摘要：目的评价磁共振血管成像（MRA）与动脉质子自旋标记（ASL）在颈内动脉系统短暂性脑缺血发作中应用价值。方法 对58例临床确诊的颈内动脉系统TIA患者进行MRA、ASL检查，并根据MRA及ASL表现对58例TIA患者进行分组分析。其中血管狭窄+ASL异常（A组）33例（56.9%），血管狭窄+ASL正常（B组）15例（25.9%），血管正常+ASL异常（C组）2例（3.5%），血管正常+ASL正常（D组）8例（13.7%）。结果 血管狭窄+ASL异常（A组）更易出现DWI高信号22/33 (66.6%)及TIA频发发作33/33，(100%）。结论 TIA患者血管狭窄合并灌注异常是TIA频发发作及可能发生严重缺血性脑卒中的最危险因素之一，MRA与ASL联合运用，可对TIA病因、预后做出判断，为TIA治疗方案的选择提供重要依据。 关键词 短暂性脑缺血 磁共振血管成像 脑灌注 MRA and ASL assess TIA patients with intracranial artery and perfusion Abstract: Objective: TO evaluate the value of magnetic resonance angiography (MRA) and arterial spin labeling proton (ASL) in the internal carotid artery transient ischemic attack. Methods: 58 Cases of clinical diagnosis of internal carotid artery system in patients with TIA accepted MRA and ASL examination, and in accordance with the performance of MRA and the ASL , 58 cases of patients with TIA accepted subgroup analysis.33 cases of patients(56.9%) with Artery stenosis and ASL abnormal(A group),15 cases of patients(25.9%) with Artery stenosis and ASL normal(B group),2 cases of patients(3.5%) with Normal vascular and ASL abnormal(C group),8 cases of patients(13.7%) with Normal vascular and ASL normal. Results: Artery stenosis and ASL abnormal(A group) were more vulnerable to high DWI signal 22/33 (66.6%) and TIA frequently attack 33/33, (100%). Conclusion: TIA patients with Artery stenosis and perfusion abnormal was one of the most risk factors of TIA may be frequent and severe attacks of ischemic stroke.The combinated application of MRA and ASL could be made to determine the Cause and Prognosis of the TIA?,then provid an important basis for the choice of TIA treatment program. Key words transient ischemic magnetic resonance angiography brain perfusion 脑血管病是严重影响人民身体健康的疾病，其中短暂性脑缺血发作（transinet ischemi attack,TIA）, 是脑梗塞明显的预警信号。由于脑组织对缺血耐受性差，一旦发生缺血，短时间内即可产生不可逆的脑损伤，因此，，将脑梗死发生后的超早期影像学研究提前到TIA的影像学研究，具有更为重要的临床价值。本研究目的是通过应用磁共振血管造影（magnetic resonance angiography,MRA）和动脉质子自旋标记（arteria