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Published online 22 July 2014 Nucleic Acids Research, 2014, Vol. 42, No. 14 8845–8860 doi: 10.1093/nar/gku555 SURVEY AND SUMMARY Single-cell RNA-seq: advances and future challenges ¨ * Antoine-Emmanuel Saliba, Alexander J. Westermann, Stanislaw A. Gorski and Jorg Vogel Institute for Molecular Infection Biology, University of Wurzburg, Josef-Schneider-Straße 2, D-97080 Wurzburg, ¨ ¨ Germany Received May 6, 2014; Revised June 02, 2014; Accepted June 8, 2014 ABSTRACT unknown species or regulatory processes (6) of biotechno- D o logical or medical relevance. w Phenotypically identical cells can dramatically vary n l Global studies of single cells have been enabled by a o a with respect to behavi
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