甲状腺功能亢进症合并肝损害的临床探讨.docVIP

甲状腺功能亢进症合并肝损害的临床探讨 谢 力1 黄泽智2 （1邵阳市中西结合医院；2邵阳医学高等专科学校 湖南 邵阳 422000） 摘 要：目的 探讨甲状腺功能亢进症合并肝损害（简称甲亢性肝损害）的临床特点。方法 将515例甲亢患者分为A组（肝功能损害组）和B组（肝功能正常组），.对A组176甲亢性肝损害患者进行正规抗甲状腺药物治疗及肝功能检查，并对前后肝功能及甲状腺激素水平进行对照分析。结果 甲亢性肝损害的发生率为34.2%，在临床上颇为多见；A组的发病年龄明显高于B组（P0.05）；肝功能损害程度与甲亢程度呈正相关（P0.01）；治疗后甲状腺激素恢复程度（△M—TSH）与肝功能恢复程度（△ALT）呈负相关（P0.01）。结论 甲亢性肝损多发于年龄较大、病情较重的患者，临床上一旦确诊为甲亢性肝损害，应早期、足量应用抗甲状腺药物治疗与护肝治疗。 关键词：甲状腺功能亢进 肝损害 甲状腺激素 The Clinical Analysis Of Hyperthyroidism Accompanied By Liver Damage Xie Li1 Huang Zezhi2 (1.Shaoyang Hospital of Integrated Traditional Chinese and Western Medicine . 2.Shaoyang Medical College ,Hunan Shaoyang 422000) Abstract：【Objective】 To investigate the clinical feature of hyperthyroidism accompanied by liver damage. 【Methods】 515 cases were divided into A group(abnormal liver function group)and B group(normal liver function group).and treated with anti-thyroid medicine and did liver function test for 176 cases of hyperthyroidism accompanied by liver damage. and compared the data of liver function and thyroin between pre-and post-therapy. 【Results】Hyperthyroidism accompanied by liver damage was rather common in clinical(about34.2%).The age of the patients of group A was significantly higher than that of group B(P0.05).The relationship between the degree of liver damage and the serious degree of hyperthyroidism was positive (P0.01).After a period of treatment the relationship between the degree of recovering from liver damage and thyroxin was negative(P0.01). 【Conclusion】 The patients with relatively old age and severe symptom, the incidence of hyperthyroidism accompanied by liver damage increases. Once we diagnosed the liver damage caused by hyperthyroidism. We should treat it with anti-thyroid medicine early，sufficiently and treat to pretect liver with some medicine. Key words： Hyperthyroidism Liver Damage Thyroid Hormone 【作者简介】：谢力（1964--）,男, 主管检验师,检验科主任,主要从事临床医学检验及教学与管理工作。 甲状腺功能亢进症（简称甲亢）是内分泌系统的多发病、常见病，可累及全身多个器官，以心血管和神经系统多见，亦可累及肝脏，引起肝肿大、肝功