Delgocitinib-ethanolate-JTE-052-ethanolate-生命科学试剂-MCE.pdf

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Delgocitinibethanolate

Cat.No.:HY-109053A

CASNo.:2064338-33-4

Synonyms:JTE-052ethanolate

分⼦式:C₁₈H₂₄N₆O₂

分⼦量:356.42

作⽤靶点:JAK

作⽤通路:Epigenetics;JAK/STATSignaling;ProteinTyrosine

Kinase/RTK;StemCell/Wnt

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Delgocitinibethanolate是⼀种特异性的JAK抑制剂，对JAK1,JAK2,JAK3和Tyk2的IC50值分别为

2.8，2.6，13和58nM[1]。

客户使⽤本产品发表的科研⽂献

•JClinMed.2020Mar24;9(3):891.

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REFERENCES

[1].TanimotoA,etal.PharmacologicalpropertiesofJTE-052:anovelpotentJAKinhibitorthatsuppressesvariousinflammatoryresponses

invitroandinvivo.InflammRes.2015Jan;64(1):41-51.

McePdfHeight

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