Sirtuin-Inhibitors-Modulators-生命科学试剂-MedChemExpress.pdf免费

Sirtuin   Sirtuin (Sir2 proteins) are a class of proteins that possess either mono-ADP-ribosyltransferase, or deacylase activity, including deacetylase, desuccinylase, demalonylase, demyristoylase and depalmitoylase activity. Sirtuins regulate important biological pathways in bacteria, archaeaand eukaryotes. Sirtuins have been implicated in influencing a wide range of cellular processes like aging, transcription, apoptosis, inflammation and stress resistance, as well as energy efficiency and alertness during low-calorie situations. Sirtuins can also control circadian clocks and mitochondrial biogenesis. www.MedChemE 1 Sirtuin Inhibitors, Activators, Agonists Modulators (R)-Selisistat (S)-Selisistat ((R)-EX-527) Cat. No.: HY-15452B ((S)-EX-527) Cat. No.: HY-15452A (R)-Selisistat ((R)-EX-527) is a R-enantiomer of (S)-Selisistat ((S)-EX-527) is a potent and Selisistat. Selisistat (EX-527) is a potent and selective SIRT1 inhibitor, with an IC50 of 98 nM. selective SIRT1 inhibitor with IC of 98 nM. 50 Purity: 98.69% Purity: 98.15% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg 3-TYP