内容分析教案st.pptxVIP

 Treatment of Genetic Diseases;Gene Therapy;;Dietary Therapy;Protein and Enzyme replacement;Protein and Enzyme replacement;Drug treatment Substitution Remove surplus Vitamine Avoidance of certain drugs or foods; ;Remove surplus for hypercholesterolemia;hydroxymethyl glutaryl co-enzyme A (HMG-CoA) reductase. LDL: low-density lipoprotein;Vitamine; Avoidance of certain drugs or foods can prevent the manifestation of the disorder For example Avoidance of Sulfonamides and broad bean is necessary for glucose-6-phosphate dehydrogenase (G6PD) deficient patients;Surgery Orthopedics ;Presymptom Therapy Familial polyposis coli. ;Transplantation renal transplantation in adult polycystic kidney disease ;Biosynthesis of Gene Products;Insulin;Gene Therapy The deliberate introduction of normal genetic material into human cells for therapeutic, prophylactic or diagnostic purposes. ;;Somatic Cell Gene therapy Manipulating the genome of somatic cells in selected tissues .The effect of the therapy are planned to be limited to the individual undergoing treatment and are not designed to introduce potentially heritable genetics modification. ;Germ line Gene therapy It is possible to permanently modify the germline of animals, which makes the young generation normally .In theory, it should be possible to do in people. ;;Physical Method Injection; The gene gun is part of a method called the biolistic (also known as bioballistic) method, and under certain conditions, DNA (or RNA) e “sticky,” adhering to biologically inert particles such as metal atoms (usually tungsten or gold). By accelerating this DNA-particle complex in a partial vacuum and placing the target tissue within the acceleration path, DNA is effectively introduced. ; Micro-particle Bombardment Micro -particle of Gold or Wolfram DNA