茅根地黄汤治疗儿童孤立性血尿的疗效观察.docVIP

福建中医学院2003级硕士研究生毕业论文 PAGE PAGE 22 茅根地黄汤治疗儿童孤立性血尿的疗效观察 专 业： 中医儿科学 研究生： 陈 惠 华 导 师： 曾 章 超 主任医师 教授 摘 要 ABSTRACT 目的：通过对茅根地黄汤治疗儿童孤立性血尿的疗效观察，旨在探讨儿童孤立性血尿的发病机制及中药治疗的作用机理，为儿童孤立性血尿的中医临床辨证施治和疗效判断提供依据。 资料与方法：选择我院2004年1月至2006年1月32例儿童孤立性血尿患儿，按简单随机法分为中药治疗组(20例）和西医对照组(12例)。治疗组采用中药(茅根地黄汤加减)治疗，对照组以西医对症治疗为主，观察两组临床疗效。 结果： 1.治疗组经过中药治疗后尿沉渣红细胞计数明显减少，治疗1个月、3个月、6个月后与治疗前相比均有非常显著差异(P0.01)；对照组治疗3个月、6个月后与治疗前相比均有显著差异(P0.05)。 2.两组间治疗前后比较：治疗前两组无显著差异，治疗1个月、3个月、6个月后尿沉渣红细胞计数均明显少于对照组(P0.05，P0.01，P0.01)。 3.疗效比较：治疗组在治疗6个月后总有效率为95%，与对照组(58.3%)比较，差异非常显著(P0.01)。 结论： 1.儿童孤立性血尿以本虚标实为主，阴虚血热是导致IH发生与发展的重要病理因素和发病机制。阴虚为本，血热为标，两者相互影响，互为因果。 2.滋阴清热凉血法是IH重要治法。若证见表、热、实证者，先去邪以急则治其标；在外邪或症情减缓或消失后，当扶正去邪、标本兼治或继以补虚扶正。 3.滋阴清热凉血法治疗儿童孤立性血尿能显著改善症状，减少尿红细胞的排泄，提高疗效。 主题词：血尿/中医药治疗 血尿/药物疗法 茅根地黄汤/治疗应用 滋阴清热凉血药/治疗应用 对比研究 儿童 CLININCAL OBSERVATION OF THE EFFECT OF LIAN GEN DI HUANG TANG IN TREATING PEDIATRIC ISOLATED HEMATURIA Major：Pediatrics of TCM Postgraduate：Chen Huihua Tutor：Prof.Zeng Zhangchao ABSTRACT Objective: To observe the curative effects of decoction Maogendihuang on peditric isolated hematuria(IH). Then to discuss the pathogenesis of isolated hematuria(IH) and the mechanisma of Chinese medication， and meanwhile to provide theoretical bases for clinical treatment of Cineses medicine based on the differentiation of symptoms of TCM and efficacy of peditric IH. Materials and methods: 32 IH patients ,who have been treated in our hospital from Oct 2004 to Jan 2006,were randomly divided into 2 group: Chinese traditional medicine treatment group and Western medicine comparison group. The treatment group patients received decoction Maogendihuang,the comparison group patients were treated with Western medicine following theirs symptom.To observe the curative effects of 2 group. Result: 1.The counts of uric sediment red blood bell are reduced obviously by treating with decoction Maogendihuang. Comparing with before treatment,there is very marked different after treat by 1 month、3 month、6 month(p﹤0